AMD Radeon PRO V620 vs NVIDIA RTX PRO 5000 Blackwell Comparison

The NVIDIA RTX PRO 5000 Blackwell is in a completely different performance class than the AMD Radeon PRO V620. In the two shared benchmark tests, the NVIDIA card wins decisively, posting scores that are roughly double those of the AMD card. The data shows a 97.6% lead in Geekbench OpenCL and a 95.8% lead in Geekbench Vulkan, making this a one-sided comparison where the RTX PRO 5000 Blackwell establishes itself as the clear performance leader.

Head-to-Head Benchmarks

The benchmark data leaves no room for ambiguity: the NVIDIA RTX PRO 5000 Blackwell dominates the AMD Radeon PRO V620 in every measurable compute workload. In the Geekbench OpenCL test, the NVIDIA card scores 254,116 against the AMD card's 128,580, a delta of 97.6%. This is not a marginal victory; it is a near-doubling of raw compute throughput. The NVIDIA card also wins the Geekbench Vulkan test with a score of 282,631 versus 144,364 for the AMD card, a 95.8% advantage. Across the two head-to-head benchmarks, NVIDIA wins 2 and AMD wins 0.

These results align with the broader performance context. The RTX PRO 5000 Blackwell holds a 98th percentile ranking among all GPUs, with an average benchmark score of 182,109. Its nearest rivals are the NVIDIA A100 SXM4 80 GB (deltaPct -0.9%), the NVIDIA RTX 5000 Ada Generation (deltaPct -1.4%), and the NVIDIA GeForce RTX 4090 D (deltaPct 2.3%). The AMD Radeon PRO V620, by contrast, sits at the 96th percentile with an average score of 136,472, and its closest competitors are the AMD Radeon Pro W6800X Duo (deltaPct 0.5%), the AMD Radeon PRO W6800 (deltaPct 0.8%), and the NVIDIA A10M (deltaPct 0.9%). The performance gap between the two cards in this comparison is far larger than the gaps between each card and its own nearest rivals, indicating that the RTX PRO 5000 Blackwell operates a full tier above the Radeon PRO V620.

Architecture Differences

The architectural divide between these two cards is stark and explains the benchmark results. The NVIDIA RTX PRO 5000 Blackwell is built on the GB202 chip using the Blackwell 2.0 architecture on a 5 nm TSMC process node. It packs 92,200 million transistors on a 750 mm² die, yielding a transistor density of 122.9M per mm². The AMD Radeon PRO V620 uses the Navi 21 chip with RDNA 2.0 architecture on a 7 nm TSMC node, containing 26,800 million transistors on a 520 mm² die with a density of 51.5M per mm². The NVIDIA card's newer process node and far higher transistor count give it a substantial raw hardware advantage.

Memory configurations differ significantly as well. The RTX PRO 5000 Blackwell features 48 GB of GDDR7 memory on a 384-bit bus, delivering 1.34 TB/s of bandwidth. The Radeon PRO V620 has 32 GB of GDDR6 memory on a 256-bit bus, providing 512.0 GB/s of bandwidth. The NVIDIA card offers 50% more memory capacity and more than 2.6 times the memory bandwidth. Clock speeds tell a more nuanced story: the AMD card has a higher base clock at 1825 MHz versus 1740 MHz, but the NVIDIA card boosts higher at 2377 MHz versus 2200 MHz. Memory clock rates also differ, with the NVIDIA card running at 1750 MHz (28 Gbps effective) and the AMD card at 2000 MHz (16 Gbps effective).

Compute resource counts are heavily lopsided. The NVIDIA card has 14,080 shading units, 440 TMUs, 160 ROPs, 110 RT cores, and 440 tensor cores. The AMD card has 4,608 shading units, 288 TMUs, 128 ROPs, and 72 RT cores, with no tensor cores listed. This translates to 66.94 TFLOPS FP32 performance for NVIDIA versus 20.28 TFLOPS for AMD. In FP16, the NVIDIA card maintains 66.94 TFLOPS (1:1 ratio), while the AMD card reaches 40.55 TFLOPS (2:1 ratio). Pixel rate is 380.3 GPixel/s for NVIDIA versus 281.6 GPixel/s for AMD, and texture rate is 1,045.9 GTexel/s versus 633.6 GTexel/s.

FAQ

Q: Which card has higher raw FP32 compute performance?

A: The NVIDIA RTX PRO 5000 Blackwell delivers 66.94 TFLOPS FP32, which is more than three times the 20.28 TFLOPS of the AMD Radeon PRO V620.

Q: How do the memory subsystems compare?

A: The NVIDIA card has 48 GB of GDDR7 on a 384-bit bus with 1.34 TB/s bandwidth, while the AMD card has 32 GB of GDDR6 on a 256-bit bus with 512.0 GB/s bandwidth.

Q: What is the process node difference?

A: The NVIDIA RTX PRO 5000 Blackwell uses a 5 nm TSMC process, while the AMD Radeon PRO V620 uses a 7 nm TSMC process. The NVIDIA chip contains 92,200 million transistors versus 26,800 million for AMD.

Q: Which card supports tensor cores?

A: Only the NVIDIA RTX PRO 5000 Blackwell lists tensor cores, with 440 of them. The AMD Radeon PRO V620 has no tensor core specification in the data.

Q: What are the physical dimensions of each card?

A: Both cards are 267 mm (10.5 inches) long. The NVIDIA card is 111 mm (4.4 inches) tall and 40 mm (1.6 inches) wide, while the AMD card is 120 mm (4.7 inches) tall and 50 mm (2 inches) wide. Both are dual-slot.

Q: What is the production status of each card?

A: The NVIDIA RTX PRO 5000 Blackwell is listed as Active, with a release date of 2025-03-17. The AMD Radeon PRO V620 is End-of-life, with a release date of 2021-11-03.

The Verdict

The data is unambiguous: the NVIDIA RTX PRO 5000 Blackwell is the superior product for any workload measured here. Its Geekbench OpenCL score of 254,116 and Vulkan score of 282,631 are roughly double the AMD Radeon PRO V620's scores of 128,580 and 144,364, respectively. The NVIDIA card also sits at the 98th percentile of all GPUs, compared to the AMD card's 96th percentile. Its average benchmark score of 182,109 is 33.4% higher than the AMD card's 136,472.

The NVIDIA card's advantages extend beyond raw benchmarks into architectural features. It has more than triple the FP32 throughput, nearly triple the memory bandwidth, and a newer process node. The AMD card's only listed advantages are a higher base clock (1825 MHz vs 1740 MHz) and a wider physical footprint. Neither of these translates into a performance win in the available data. For anyone choosing between these two based on the benchmark results, the NVIDIA RTX PRO 5000 Blackwell is the clear pick. The AMD Radeon PRO V620, while a capable card in its own right as shown by its 96th percentile ranking, is simply outclassed in this direct comparison.

Specification Differences

The two cards differ across nearly every major specification category. The NVIDIA RTX PRO 5000 Blackwell uses a GB202 chip on the Blackwell 2.0 architecture, while the AMD Radeon PRO V620 uses a Navi 21 chip on RDNA 2.0. Process nodes differ: 5 nm for NVIDIA versus 7 nm for AMD. Transistor counts are 92,200 million versus 26,800 million, and die sizes are 750 mm² versus 520 mm². Transistor density is 122.9M per mm² for NVIDIA and 51.5M per mm² for AMD.

Memory specifications diverge completely. The NVIDIA card has 48 GB GDDR7 with a 384-bit bus and 1.34 TB/s bandwidth. The AMD card has 32 GB GDDR6 with a 256-bit bus and 512.0 GB/s bandwidth. Clock speeds differ: NVIDIA base is 1740 MHz with a 2377 MHz boost, while AMD base is 1825 MHz with a 2200 MHz boost. Memory clocks are 1750 MHz (28 Gbps effective) for NVIDIA and 2000 MHz (16 Gbps effective) for AMD.

Compute resources are heavily imbalanced. NVIDIA has 14,080 shading units, 440 TMUs, 160 ROPs, 110 RT cores, and 440 tensor cores. AMD has 4,608 shading units, 288 TMUs, 128 ROPs, and 72 RT cores, with no tensor cores. Pixel rate is 380.3 GPixel/s versus 281.6 GPixel/s, and texture rate is 1,045.9 GTexel/s versus 633.6 GTexel/s. FP32 is 66.94 TFLOPS versus 20.28 TFLOPS, and FP16 is 66.94 TFLOPS (1:1) versus 40.55 TFLOPS (2:1).

Other differences include bus interface (PCIe 5.0 x16 versus PCIe 4.0 x16), display outputs (4x DisplayPort 2.1b versus no outputs), power connectors (1x 16-pin versus 2x 8-pin), and dimensions (NVIDIA is shorter and narrower). Both cards have 300 W TDP, require a 700 W PSU, are dual-slot, and support DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4.

Where Each One Wins

The NVIDIA RTX PRO 5000 Blackwell wins in every benchmark category where both cards have data. It wins the Geekbench OpenCL test by 97.6% and the Geekbench Vulkan test by 95.8%. Its 48 GB memory capacity and 1.34 TB/s bandwidth make it the better choice for large dataset workloads. Its 440 tensor cores and 66.94 TFLOPS FP32 performance position it for compute-heavy tasks. The card's Active production status and 2025 release date also indicate it is the more current option.

The AMD Radeon PRO V620 does not win any head-to-head benchmark. Its strengths are limited to specific specification areas: it has a higher base clock speed (1825 MHz vs 1740 MHz), a higher memory clock in MHz (2000 MHz vs 1750 MHz), and a taller and wider physical profile. Its End-of-life production status and 2021 release date suggest it is a legacy product. The card's 96th percentile ranking shows it is still a solid performer relative to the broader GPU market, but in this direct comparison, it has no performance category where it emerges victorious. For workloads that depend purely on the benchmark metrics available, the NVIDIA RTX PRO 5000 Blackwell is the only rational choice.