AMD Radeon PRO V620 vs NVIDIA Quadro P6000 Comparison

Head-to-Head Benchmarks

The recorded data shows a decisive performance gap between these two professional workstation cards. In the Geekbench OpenCL test, the AMD Radeon PRO V620 scores 128,580 against the NVIDIA Quadro P6000's 66,382, a 93.7% advantage for the AMD part. The Vulkan benchmark widens that margin further: the Radeon PRO V620 reaches 144,364 while the Quadro P6000 manages 73,590, a 96.2% lead. These are not marginal differences; the AMD card nearly doubles the NVIDIA card's compute output in both API tests.

Looking at the broader database context, the Radeon PRO V620's average benchmark score of 136,472 places it in the 96th percentile of all GPUs, while the Quadro P6000's 69,986 average sits in the 90th percentile. The AMD card sits within 0.5% of the AMD Radeon Pro W6800X Duo, 0.8% of the AMD Radeon PRO W6800, 0.9% of the NVIDIA A10M, and 0.9% of the NVIDIA RTX 4000 Ada Generation. The Quadro P6000, by contrast, is within 0.2% of the AMD Radeon Pro WX 8200, within 0.2% of the NVIDIA RTX A3000 Mobile (which edges it out), and within 1.2% of the AMD Radeon RX 6600 LE. The performance stratification is clear: the Radeon PRO V620 competes in a higher performance tier entirely.

The head-to-head results are unambiguous. The Radeon PRO V620 wins both recorded benchmarks, earning 2 wins against 0 for the Quadro P6000. The delta percentages (93.7% in OpenCL, 96.2% in Vulkan) indicate that the AMD architecture delivers nearly double the throughput in these synthetic workloads. This is not a case where one card wins narrowly in one test and loses narrowly in another; the Radeon PRO V620 dominates across both APIs.

Where Each One Wins

The Radeon PRO V620's advantages are rooted in raw compute capability. Its FP32 throughput of 20.28 TFLOPS dwarfs the Quadro P6000's 12.63 TFLOPS, a 60.6% difference in peak single-precision performance. The FP16 gap is even more extreme: the Radeon PRO V620 delivers 40.55 TFLOPS (2:1 ratio) versus the Quadro P6000's 197.4 GFLOPS (1:64 ratio). This means the AMD card offers over 200 times the half-precision throughput, making it substantially more suited for workloads that leverage FP16 acceleration, such as AI inference or certain scientific computing tasks.

Memory capacity and bandwidth also favor the AMD card. The Radeon PRO V620 comes with 32 GB of GDDR6 memory on a 256-bit bus, yielding 512.0 GB/s of bandwidth. The Quadro P6000 offers 24 GB of GDDR5X on a 384-bit bus, producing 432.8 GB/s. While the NVIDIA card has a wider memory interface, the AMD card's faster memory clock (2000 MHz, 16 Gbps effective versus 1127 MHz, 9 Gbps effective) compensates, resulting in higher total bandwidth. For large dataset manipulation or rendering tasks that saturate memory bandwidth, the Radeon PRO V620 holds the edge.

The Quadro P6000's remaining strengths are narrower. It features display outputs (1x DVI, 4x DisplayPort 1.4a), whereas the Radeon PRO V620 has no display outputs at all, making it a compute-only accelerator. The Quadro P6000 also requires a single 8-pin power connector versus the AMD card's two 8-pin connectors, and its 250 W TDP is lower than the Radeon PRO V620's 300 W. The NVIDIA card's PCIe 3.0 x16 interface is older than the AMD card's PCIe 4.0 x16, but for systems without PCIe 4.0 support this is a non-issue. In terms of raw benchmark performance, the Quadro P6000 does not win any recorded test; its value lies in its legacy ecosystem, display connectivity, and lower power envelope.

Architecture Differences

The two cards represent fundamentally different architectural generations. The AMD Radeon PRO V620 uses the Navi 21 chip built on RDNA 2.0 architecture, fabricated on TSMC's 7 nm process. It packs 26,800 million transistors into a 520 mm² die, yielding a transistor density of 51.5M per mm². The NVIDIA Quadro P6000 uses the GP102 chip on the older Pascal architecture, built on TSMC's 16 nm process. It contains 11,800 million transistors on a 471 mm² die, for a density of 25.1M per mm². The AMD chip has more than double the transistor count and over twice the density, enabled by the smaller process node.

The compute resources differ substantially. The Radeon PRO V620 has 4,608 shading units, 288 texture mapping units, and 128 raster output pipelines, plus 72 ray tracing cores. The Quadro P6000 has 3,840 shading units, 240 TMUs, and 96 ROPs, with no ray tracing cores. The AMD card's pixel rate of 281.6 GPixel/s and texture rate of 633.6 GTexel/s compare favorably to the NVIDIA card's 157.9 GPixel/s and 394.8 GTexel/s. The RDNA 2.0 architecture also includes hardware ray tracing support, which Pascal lacks entirely.

Memory technology differs as well. The Radeon PRO V620 uses GDDR6 with a 256-bit bus and 512.0 GB/s bandwidth, while the Quadro P6000 uses GDDR5X with a 384-bit bus and 432.8 GB/s bandwidth. The AMD card's memory runs at 2000 MHz (16 Gbps effective) versus the NVIDIA card's 1127 MHz (9 Gbps effective). The AMD card also supports DirectX 12 Ultimate (12_2), while the Quadro P6000 tops out at DirectX 12 (12_1). Both support OpenGL 4.6 and Vulkan 1.4.

The bus interface differs as well: PCIe 4.0 x16 on the AMD card versus PCIe 3.0 x16 on the NVIDIA card. The AMD card is a compute-only accelerator with no display outputs, whereas the NVIDIA card provides 1x DVI and 4x DisplayPort 1.4a outputs. Physically, both are dual-slot cards with 267 mm length, but the AMD card is taller (120 mm versus 111 mm) and wider (50 mm versus unspecified width for the NVIDIA card).

FAQ

Q: Which card has higher benchmark scores?

A: The AMD Radeon PRO V620 dominates. In Geekbench OpenCL, it scores 128,580 versus the Quadro P6000's 66,382, a 93.7% advantage. In Geekbench Vulkan, it scores 144,364 versus 73,590, a 96.2% lead.

Q: Does the Quadro P6000 have any ray tracing capability?

A: No. The Quadro P6000's Pascal architecture has no ray tracing cores. The Radeon PRO V620 includes 72 ray tracing cores on its RDNA 2.0 architecture.

Q: What is the memory configuration difference?

A: The Radeon PRO V620 has 32 GB of GDDR6 on a 256-bit bus with 512.0 GB/s bandwidth. The Quadro P6000 has 24 GB of GDDR5X on a 384-bit bus with 432.8 GB/s bandwidth.

Q: Can the Radeon PRO V620 drive displays?

A: No. The Radeon PRO V620 has no display outputs, making it a compute-only accelerator. The Quadro P6000 provides 1x DVI and 4x DisplayPort 1.4a outputs.

Q: How do their power requirements compare?

A: The Radeon PRO V620 has a 300 W TDP and requires two 8-pin power connectors, with a suggested 700 W power supply. The Quadro P6000 has a 250 W TDP, requires one 8-pin connector, and suggests a 600 W power supply.

Q: Which card has better FP16 performance?

A: The Radeon PRO V620 delivers 40.55 TFLOPS FP16 (2:1 ratio), while the Quadro P6000 offers only 197.4 GFLOPS FP16 (1:64 ratio). The AMD card has over 200 times the half-precision throughput.

Specification Differences

| Specification | AMD Radeon PRO V620 | NVIDIA Quadro P6000 |

|---|---|---|

| Architecture | RDNA 2.0 | Pascal |

| Process Node | 7 nm | 16 nm |

| Transistors | 26,800 million | 11,800 million |

| Die Size | 520 mm² | 471 mm² |

| Transistor Density | 51.5M / mm² | 25.1M / mm² |

| Base Clock | 1825 MHz | 1506 MHz |

| Boost Clock | 2200 MHz | 1645 MHz |

| Memory Clock | 2000 MHz (16 Gbps effective) | 1127 MHz (9 Gbps effective) |

| Memory Size | 32 GB | 24 GB |

| Memory Type | GDDR6 | GDDR5X |

| Memory Bus Width | 256 bit | 384 bit |

| Memory Bandwidth | 512.0 GB/s | 432.8 GB/s |

| Shading Units | 4608 | 3840 |

| TMUs | 288 | 240 |

| ROPs | 128 | 96 |

| RT Cores | 72 | None |

| Pixel Rate | 281.6 GPixel/s | 157.9 GPixel/s |

| Texture Rate | 633.6 GTexel/s | 394.8 GTexel/s |

| FP32 Performance | 20.28 TFLOPS | 12.63 TFLOPS |

| FP16 Performance | 40.55 TFLOPS (2:1) | 197.4 GFLOPS (1:64) |

| TDP | 300 W | 250 W |

| Power Connectors | 2x 8-pin | 1x 8-pin |

| Suggested PSU | 700 W | 600 W |

| Bus Interface | PCIe 4.0 x16 | PCIe 3.0 x16 |

| Display Outputs | No outputs | 1x DVI, 4x DisplayPort 1.4a |

| DirectX Support | 12 Ultimate (12_2) | 12 (12_1) |

| Release Date | 2021-11-03 | 2016-09-30 |

| Predecessor | Radeon Pro Vega | Quadro Maxwell |

| Successor | None | Quadro Volta |

| Production Status | End-of-life | End-of-life |

| Launch MSRP | None recorded | 5,999 USD |

The specification table confirms the architectural generational gap. The Radeon PRO V620 is newer, denser, faster in every compute metric, and offers more memory. The Quadro P6000 retains advantages only in display connectivity, lower power draw, and single-connector power requirements. The benchmark results reflect these differences: the Radeon PRO V620's average score of 136,472 is nearly double the Quadro P6000's 69,986, and the percentile ranking difference (96th versus 90th) places them in different performance classes entirely. For workloads that leverage FP16, ray tracing, or high-bandwidth memory, the Radeon PRO V620 is the clear choice based on the recorded data. For systems requiring direct display output from the GPU, the Quadro P6000's connectivity is a functional advantage, though its compute performance lags significantly.