AMD Radeon Pro 575X vs NVIDIA GeForce RTX 4080 SUPER Comparison

Head-to-Head Benchmarks

The recorded data shows a decisive performance gap between these two cards. In Geekbench OpenCL, the NVIDIA GeForce RTX 4080 SUPER scores 219,065 against 34,773 for the AMD Radeon Pro 575X. That is a 530% advantage. In Geekbench Vulkan, the gap widens further: 260,075 versus 37,919, a 585.9% lead for the NVIDIA card. Both head-to-head tests go to the RTX 4080 SUPER, with zero wins recorded for the AMD part.

To put these numbers in context, the RTX 4080 SUPER sits at the 86th percentile of all GPUs in the database, with an average benchmark score of 54,209. Its closest rival in the database is the NVIDIA GeForce RTX 4080, which averages 54,247, a minuscule 0.1% difference. The AMD Radeon Pro W5700X trails by 1.1%, and the AMD Radeon RX 6750 GRE 12 GB by 2.7%. In other words, the RTX 4080 SUPER is at the top of a very tight cluster of high-end cards.

The AMD Radeon Pro 575X, by contrast, holds the 82nd percentile and averages 39,116 across its recorded benchmarks. Its nearest rival is the AMD Radeon Pro 575 at 39,555, which is 1.1% faster. The AMD Radeon Pro 580X and NVIDIA GeForce MX570 A both sit about 1.1% behind. The 575X is competitive within its own generation of professional mobile and workstation parts, but that generation is simply not in the same performance class as the RTX 4080 SUPER.

The raw score difference is not subtle. In OpenCL, the RTX 4080 SUPER delivers more than six times the score of the 575X. In Vulkan, it is nearly seven times. These are not incremental improvements; they represent a completely different performance tier. The RTX 4080 SUPER's average benchmark score of 54,209 is roughly 38.6% higher than the 575X's 39,116, even before isolating the head-to-head tests.

Where Each One Wins

The RTX 4080 SUPER wins in every recorded benchmark category where both cards have data. In OpenCL, it is 530% ahead. In Vulkan, it is 585.9% ahead. There is no test in the database where the AMD Radeon Pro 575X posts a higher score. That said, the 575X has one benchmark in the database that the RTX 4080 SUPER does not: Geekbench Metal, where it scores 44,655. This indicates the AMD card was designed with Apple ecosystem workloads in mind, likely for Mac Pro systems, and its Metal performance is the only area where it has a recorded presence that the NVIDIA card lacks.

For compute-heavy tasks using OpenCL or Vulkan, the RTX 4080 SUPER is clearly the superior choice. Its 52.22 TFLOPS FP32 throughput and 736.3 GB/s memory bandwidth dwarf the 575X's 4.489 TFLOPS and 217.0 GB/s. The RTX 4080 SUPER also has 16 GB of GDDR6X memory versus 4 GB of GDDR5, which matters for large datasets and high-resolution textures. The NVIDIA card supports DirectX 12 Ultimate (12_2), while the AMD card is limited to DirectX 12 (12_0). Vulkan support is also newer on the NVIDIA side: 1.4 versus 1.3.

The AMD Radeon Pro 575X, on the other hand, is a 150 W part with no external power connectors, designed as an integrated GPU option for portable devices. Its display outputs are listed as "Portable Device Dependent," meaning it is not a standalone card you would install in a desktop. Its niche is professional Mac workflows where the system is already specified, and where Metal performance is the relevant metric. In that narrow context, it has a role. But for anyone choosing between these two cards for general compute, rendering, or gaming, the data points overwhelmingly to the RTX 4080 SUPER.

FAQ

Q: How much faster is the RTX 4080 SUPER than the Radeon Pro 575X in OpenCL?

A: The RTX 4080 SUPER scores 219,065 in Geekbench OpenCL, while the Radeon Pro 575X scores 34,773. That is a 530% advantage for the NVIDIA card.

Q: Does the Radeon Pro 575X win in any benchmark?

A: No. In the head-to-head tests recorded in the database, the RTX 4080 SUPER wins both OpenCL and Vulkan. The 575X has a Geekbench Metal score of 44,655 in the database, but the RTX 4080 SUPER has no Metal score recorded, so there is no direct comparison available.

Q: How close is the RTX 4080 SUPER to its nearest rival in the database?

A: The NVIDIA GeForce RTX 4080 averages 54,247, which is only 0.1% behind the RTX 4080 SUPER's 54,209. The AMD Radeon Pro W5700X is 1.1% behind, and the AMD Radeon RX 6750 GRE 12 GB is 2.7% behind.

Q: What are the memory specifications of each card?

A: The RTX 4080 SUPER has 16 GB of GDDR6X memory with a 256-bit bus width and 736.3 GB/s bandwidth. The Radeon 575X has 4 GB of GDDR5, also on a 256-bit bus, with 217.0 GB/s bandwidth.

Q: What is the production status of these cards in the database?

A: Both are listed as end-of-life. The RTX 4080 SUPER was succeeded by the GeForce 50 series and has a recorded launch MSRP of 999 USD. The Radeon Pro 575X has no successor listed.

Specification Differences

The RTX 4080 SUPER uses the AD103 chip with Ada Lovelace architecture on a 5 nm TSMC process node, with 45,900 million transistors on a die size of 379 mm². The Radeon Pro 575X uses the Ellesmere chip with GCN 4.0 architecture on a 14 nm GlobalFoundries process node, with 5,700 million transistors on a 232 mm² die. Transistor density is 121.1 million per mm² for NVIDIA and 24.6 million per mm² for AMD. The RTX 4080 SUPER has 10,240 shading units, 320 TMUs, and 112 ROPs, while the 575X has 2,048 shading units, 128 TMUs, and 32 ROPs. The NVIDIA card has 80 RT cores and 320 tensor cores; the AMD card has none listed. Pixel rate is 285.6 GPixel/s versus 35.07 GPixel/s. Texture rate is 816.0 GTexel/s versus 140.3 GTexel/s. FP32 throughput is 52.22 TFLOPS versus 4.489 TFLOPS. FP16 is identical in ratio on both, at 1:1.

The NVIDIA card has a base clock of 2295 MHz and boost of 2550 MHz, with memory clocked at 1438 MHz 23 Gbps effective. The AMD card has no base clock listed, no boost clock listed, and memory at 1695 MHz at 6.8 Gbps effective. TDP is 320 W versus 150 W. The RTX 4080 SUPER is triple-slot with 1x 16-pin power and a suggested PSU of 700 W. The 575X is an IGP class with no power connectors and no suggested PSU listed. Bus interface is PCIe 4.0 x16 for NVIDIA, PCIe 3.0 x16 for AMD. Display outputs differ as well: the RTX 4080 SUPER has 1x HDMI 2.13x DisplayPort 1.4a, while the 575X is portable device dependent. The RTX 4080 SUPER is 310 mm long, 140 mm high, and 61 mm wide; the AMD card has no dimensions listed. For APIs, the RTX 4080 SUPER has DirectX 12 Ultimate (12_2) and OpenGL 4.6, and Vulkan 1.4. The AMD card has DirectX 12 (12_0), OpenGL 4.3, and Vulkan 1.3.

Architecture Differences

The architecture gap is fundamental, not just a difference in clock speed or memory size. The RTX 4080 SUPER's Ada Lovelace design includes dedicated RT cores and tensor cores, enabling hardware-accelerated ray tracing and AI workloads. The GCN 4.0 architecture in the 575X predates these features entirely; it has no RT cores listed and no tensor cores listed. The NVIDIA card supports DirectX 12 Ultimate Ultimate (12_2), which includes features like variable rate shading and mesh shaders, while the 575X is limited to DirectX 12 (12_0). The newer process node, 5 nm versus 14 nm, and the presence of GDDR6X memory versus GDDR5, are additional markers of the 4080 SUPER's architecture being from a later era. The RTX 4080 SUPER is built on the GeForce 40-series generation, released in 2024, while the 575X is from the Radeon Pro 500X Series for Mac lineup, released in 2019. The 575X uses a much smaller die, with fewer transistors, and the 4080 SUPER has 8 times the shading units, 2.5 times the TMUs, and 3.5 times the ROPs.

The RTX 4080 SUPER has a higher texture rate and pixel rate, and it supports Vulkan 1.4, while the 575X is at Vulkan 1.3. The 575X's memory clock is also lower, at 1695 MHz effective 6.8 Gbps, while the 4080 SUPER runs at 1438 MHz effective 23 Gbps, with the higher effective bandwidth of GDDR6X. The 575X is designed to fit into a portable device, with no dimensions listed and no power connectors, while the 4080 SUPER is a full triple-slot card. The 575X has no power connector and a TDP of 150 W, while the 4080 SUPER draws 320 W, and the 4080 SUPER has a bus interface of PCIe 4.0 x16, the 575X uses PCIe 3.0. The 575X integrated GPU slot width is IGP. The transistor count difference, and the 5 nm process, reflect the 4080 SUPER's much larger die size, with 45,900 million versus 5,700 million transistors.

The 4080 SUPER has a transistor density of 121.1 million per mm², the 575X has 24.6 million per mm². The 4080 SUPER has a 256-bit bus, the 575X has a 256-bit bus, but the 4080 SUPER has 16 GB of GDDR6X memory, 575X has 4 GB of GDDR5, and the 4080 SUPER has 80 RT cores, 320 tensor cores. The 4080 SUPER has 320 TMUs, 112 ROPs. 575X has 112 ROPs. The 4080 SUPER has 112 ROPs. The 575X has 32 ROPs. The 4080 SUPER has a 285.6 GPixel/s pixel rate, the 575X has a 35.07 GPixel/s pixel rate. The 4080 SUPER has 816 GTexel/s texture rate, 575X has 140.3 GTexel/s. The 4080 SUPER FP32 52.22 TFLOPS, 575X FP32 4.489 TFLOPS.

The Verdict

For anyone building or specifying a high-end desktop workstation, the RTX 4080 SUPER is the only defensible pick from the data. It wins every head-to-head benchmark recorded: 530% in OpenCL, 585.9% in Vulkan. It has 16 GB of GDDR6X memory, 736.3 GB/s bandwidth, 52.22 TFLOPS FP32. It is a triple-slot card, with a 320W TDP, and it is in the 86th percentile of all GPUs. For any workload in the database that involves OpenCL compute, Vulkan rendering, DirectX 12, or DirectX 11, the RTX 4080 SUPER literally outperforms the 575X by an order of magnitude.

The AMD Radeon Pro 575X is for a different kind of buyer entirely: a professional user locked into the Apple Mac ecosystem, likely a Mac Pro user who needs Metal performance and cannot use an NVIDIA card for that workload. The 575X has no recorded wins against the RTX 4080 SUPER, but it also has a unique Geekbench Metal score of 44,655, which is the only benchmark in the database that the RTX 4080 SUPER does not have. It is a 150 W IGP part with no power connectors, and its display outputs are portable device dependent. It is at the 82nd percentile, and its nearest rival is the AMD Radeon Pro 575 at 1.4% faster. If you are in the 500X Mac Pro market, the 575X is a capable, if dated, card. If you are comparing performance across the entire database, the RTX 4080 SUPER is in a different league. The data is unambiguous.