AMD Instinct MI355X vs NVIDIA RTX PRO 4000 Blackwell SFF Comparison

Head-to-Head Benchmarks

The recorded database contains no direct head-to-head benchmark results between the AMD Instinct MI355X and the NVIDIA RTX PRO 4000 Blackwell SFF. The AMD Instinct MI355X has an average benchmark score of 0, with no individual benchmark entries, while the NVIDIA RTX PRO 4000 Blackwell SFF has a single recorded benchmark result. In 3DMark Steel Nomad DX12, the NVIDIA card scores 2910 points. This places it at the 19th percentile among all GPUs in the database, indicating that it outperforms roughly one-fifth of recorded graphics cards in this specific test.

The NVIDIA card's nearest rivals in the database provide context for its performance tier. The NVIDIA GeForce RTX 4060 Ti 16 GB scores 2907, which is 0.1% lower than the RTX PRO 4000 Blackwell SFF. The NVIDIA GeForce RTX 4060 Ti 8 GB scores 2913, 0.1% higher. The NVIDIA Quadro P600 scores 2923, 0.4% higher, and the NVIDIA GeForce RTX 4010 scores 2893, 0.6% lower. These margins are extremely tight, all within 1% of each other. The data shows the RTX PRO 4000 Blackwell SFF sits squarely in a performance cluster with these consumer and professional cards, neither leading nor trailing its immediate competitors by any meaningful margin.

For the AMD Instinct MI355X, the absence of benchmark scores means the database cannot currently quantify its performance in any standardized test. The percentile ranking of 50 for the AMD card is a neutral placeholder, not an indication of measured performance. Any direct comparison between the two cards in this section would require data that has not been recorded.

The Verdict

The database presents two products with fundamentally different intended workloads and no overlapping benchmark data. The NVIDIA RTX PRO 4000 Blackwell SFF has a verified 3DMark Steel Nomad DX12 score of 2910, placing it at the 19th percentile overall. Its nearest rivals in the database, the RTX 4060 Ti variants and the Quadro P600, all score within 0.6% of it. This indicates that in this particular synthetic graphics test, the card performs on par with mid-range consumer GPUs from the same manufacturer.

The AMD Instinct MI355X has no recorded benchmarks, so its performance profile cannot be established from the database. The card is designed for a different segment altogether, as its specifications suggest. The NVIDIA card, by contrast, has a production status of Active, meaning it is currently available, while the AMD card's production status is not recorded.

Data-driven selection depends entirely on the workload. For tasks that align with the 3DMark Steel Nomad DX12 benchmark, the NVIDIA RTX PRO 4000 Blackwell SFF has demonstrated measurable results. For tasks involving large memory capacities or massive compute throughput, the AMD Instinct MI355X presents specifications that the NVIDIA card cannot match, but those specifications have not been validated by benchmark scores. The database does not support a definitive winner, only a clear division of capabilities.

Architecture Differences

The AMD Instinct MI355X uses the MI350 256CU chip built on TSMC's 3 nm process, featuring the CDNA 4.0 architecture. It belongs to the Instinct (MIx) generation. The chip contains 185,000 million transistors on a die size of 2380 mm², resulting in a transistor density of 77.7 million per mm². The NVIDIA RTX PRO 4000 Blackwell SFF uses the GB203 chip on TSMC's 5 nm process, featuring the Blackwell 2.0 architecture. It belongs to the Blackwell PRO W (x000) generation. The chip contains 45,600 million transistors on a die size of 378 mm², resulting in a transistor density of 120.6 million per mm².

The AMD chip is substantially larger in both transistor count and physical area, but the NVIDIA chip achieves a higher transistor density due to its smaller process node advantage being offset by the AMD chip's much larger scale. The AMD card uses 16,384 shading units, 1,024 texture mapping units, and no ROPs, with a pixel rate of 0 MPixel/s. The NVIDIA card uses 8,960 shading units, 280 texture mapping units, and 96 ROPs, with a pixel rate of 128.8 GPixel/s. The NVIDIA card also includes 70 ray tracing cores and 280 tensor cores, while the AMD card lists no RT cores and no tensor cores in the database.

The AMD card reports a texture rate of 2,457.6 GTexel/s, while the NVIDIA card reports 375.8 GTexel/s. The AMD card's FP32 performance is 78.64 TFLOPS, and its FP16 performance is also 78.64 TFLOPS at a 1:1 ratio. The NVIDIA card's FP32 performance is 24.05 TFLOPS, with FP16 also at 24.05 TFLOPS at a 1:1 ratio. The AMD card has no display outputs, while the NVIDIA card has 4x mini-DisplayPort 2.1b connectors. The NVIDIA card supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, while the AMD card lists N/A for all three APIs.

Specification Differences

The AMD Instinct MI355X has a base clock of 1000 MHz and a boost clock of 2400 MHz, while the NVIDIA RTX PRO 4000 Blackwell SFF has a base clock of 405 MHz and a boost clock of 1342 MHz. Memory clocks differ as well: the AMD card runs at 2000 MHz with 8 Gbps effective speed, while the NVIDIA card runs at 1125 MHz with 18 Gbps effective speed. The AMD card uses 288 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The NVIDIA card uses 24 GB of GDDR7 memory on a 192-bit bus, delivering 432.0 GB/s of bandwidth.

The AMD card has a thermal design power of 1400 W and requires a suggested PSU of 1800 W, while the NVIDIA card has a TDP of 70 W and requires a suggested PSU of 250 W. The AMD card uses an OAM module slot width with no power connectors, while the NVIDIA card uses a dual-slot design with no power connectors. The AMD card uses a PCIe 5.0 x16 interface, while the NVIDIA card uses PCIe 5.0 x8.

Physical dimensions differ substantially. The AMD card measures 102 mm in length and 165 mm in width, with no recorded height. The NVIDIA card measures 167 mm in length, 69 mm in height, and 40 mm in width. The NVIDIA card has a recorded release date of August 10, 2025, while the AMD card has a release date of June 11, 2025. The NVIDIA card's predecessor is listed as Workstation Ada, while the AMD card's predecessor is Radeon Instinct. Neither card has a successor listed in the database.

FAQ

Q: Which card has higher FP32 compute performance?

A: The AMD Instinct MI355X delivers 78.64 TFLOPS of FP32 performance, which is more than three times the 24.05 TFLOPS of the NVIDIA RTX PRO 4000 Blackwell SFF.

Q: How much memory does each card provide?

A: The AMD Instinct MI355X has 288 GB of HBM3e memory on an 8192-bit bus, while the NVIDIA RTX PRO 4000 Blackwell SFF has 24 GB of GDDR7 memory on a 192-bit bus.

Q: What is the power consumption difference?

A: The AMD Instinct MI355X has a TDP of 1400 W and requires a suggested PSU of 1800 W, while the NVIDIA RTX PRO 4000 Blackwell SFF has a TDP of 70 W and requires a suggested PSU of 250 W.

Q: Does the NVIDIA card support ray tracing?

A: The NVIDIA RTX PRO 4000 Blackwell SFF includes 70 ray tracing cores and 280 tensor cores, while the AMD Instinct MI355X lists no RT cores and no tensor cores in the database.

Q: What display outputs does each card have?

A: The NVIDIA RTX PRO 4000 Blackwell SFF has 4x mini-DisplayPort 2.1b outputs, while the AMD Instinct MI355X has no display outputs.

Q: How does the NVIDIA card compare to its nearest rivals in the database?

A: The RTX PRO 4000 Blackwell SFF scores 2910 in 3DMark Steel Nomad DX12, which is 0.1% higher than the RTX 4060 Ti 16 GB, 0.1% lower than the RTX 4060 Ti 8 GB, 0.4% lower than the Quadro P600, and 0.6% higher than the RTX 4010.

Where Each One Wins

The AMD Instinct MI355X wins decisively in memory capacity and bandwidth. Its 288 GB of HBM3e memory dwarfs the 24 GB of GDDR7 in the NVIDIA card, and its 8.19 TB/s bandwidth is nearly 19 times higher than the NVIDIA card's 432.0 GB/s. The AMD card also wins in raw compute throughput, with 78.64 TFLOPS in both FP32 and FP16, compared to 24.05 TFLOPS in both for the NVIDIA card. The AMD card's texture rate of 2,457.6 GTexel/s is over six times higher than the NVIDIA card's 375.8 GTexel/s.

The NVIDIA RTX PRO 4000 Blackwell SFF wins in areas that the AMD card does not address. It has display outputs, specifically 4x mini-DisplayPort 2.1b, while the AMD card has none. The NVIDIA card supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, while the AMD card lists no API support. The NVIDIA card has 96 ROPs and a pixel rate of 128.8 GPixel/s, while the AMD card has 0 ROPs and a pixel rate of 0 MPixel/s. The NVIDIA card also includes 70 RT cores and 280 tensor cores, which the AMD card lacks entirely.

The NVIDIA card wins in power efficiency and physical footprint. Its 70 W TDP is 20 times lower than the AMD card's 1400 W, and its suggested PSU of 250 W is far below the AMD card's 1800 W requirement. The NVIDIA card is a dual-slot design measuring 167 mm by 69 mm by 40 mm, while the AMD card is an OAM module measuring 102 mm by 165 mm. The NVIDIA card also has a higher transistor density at 120.6 million per mm², compared to 77.7 million per mm² for the AMD card.

The NVIDIA card is the only one of the two with a recorded benchmark score. Its 2910 in 3DMark Steel Nomad DX12 places it at the 19th percentile among all GPUs, with nearest rivals all within 0.6% of its score. The AMD card has no benchmark data, so its actual performance in any standardized test remains unrecorded. The database shows two products optimized for entirely different roles: the AMD card for massive compute and memory workloads, the NVIDIA card for graphics rendering and workstation tasks with display output and API support.