AMD Instinct MI355X vs NVIDIA RTX PRO 4000 Blackwell Comparison

# FAQ

Q: What is the average benchmark score for each product in the database?

A: The AMD Instinct MI355X has an average benchmark score of 0, while the NVIDIA RTX PRO 4000 Blackwell records an average score of 27135. The database does not list any individual benchmark results for the AMD part.

Q: How does the NVIDIA RTX PRO 4000 Blackwell compare to its nearest rivals in average score?

A: The RTX PRO 4000 Blackwell sits 1.1% below the AMD Radeon RX 6700 XT (score 27425) and the NVIDIA GeForce RTX 4070 Mobile (score 27435). It trails the GeForce RTX 3090 (score 27565) by 1.6%, while it leads the NVIDIA RTX A4000 (score 26683) by 1.7%.

Q: What is the transistor density of each chip?

A: The AMD MI355X uses a 3 nm process with 185,000 million transistors on a 2380 mm² die, yielding a density of 77.7M transistors per mm². The NVIDIA RTX PRO 4000 Blackwell uses a 5 nm process with 45,600 million transistors on a 378 mm² die, for a density of 120.6M per mm².

Q: What memory configurations do the two cards use?

A: The AMD Instinct MI355X features 288 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s bandwidth. The NVIDIA RTX PRO 4000 Blackwell has 24 GB of GDDR7 memory on a 192-bit bus, providing 672.0 GB/s bandwidth.

Q: Which card supports display outputs?

A: The NVIDIA RTX PRO 4000 Blackwell includes 4x DisplayPort 2.1b outputs. The AMD Instinct MI355X has no display outputs, as it is designed as an OAM module for compute-focused deployments.

Q: What is the release date for each product?

A: The AMD Instinct MI355X was released on 2025-06-11, while the NVIDIA RTX PRO 4000 Blackwell was released earlier on 2025-03-17.

# Architecture Differences

The AMD Instinct MI355X and NVIDIA RTX PRO 4000 Blackwell diverge fundamentally in their architectural goals. The AMD part uses the CDNA 4.0 architecture, built on the MI350 256CU chip, and is fabricated on a 3 nm process at TSMC. This is a compute-optimized design with no rendering pipeline: it has 0 ROPs, no display outputs, and no DirectX, OpenGL, or Vulkan API support. The NVIDIA part uses the Blackwell 2.0 architecture on the GB203 chip, manufactured on a 5 nm process, and is explicitly a workstation GPU with full graphics capabilities, including DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4 support.

The transistor counts highlight the scale difference. The MI355X packs 185,000 million transistors across a 2380 mm² die, while the RTX PRO 4000 Blackwell integrates 45,600 million transistors on a 378 mm² die. Despite the larger die, the MI355X has a lower transistor density at 77.7M per mm² compared to 120.6M per mm² for the Blackwell chip, indicating a less dense but vastly larger implementation.

Shading unit counts also differ sharply. The MI355X has 16,384 shading units and 1,024 texture mapping units, but no ROPs, which confirms its non-rasterized compute focus. The RTX PRO 4000 Blackwell carries 8,960 shading units, 280 TMUs, 96 ROPs, 70 RT cores, and 280 tensor cores, giving it a complete geometry-to-pixel pipeline. The AMD part has no RT or tensor core counts listed in the database, reinforcing its role as a pure compute accelerator.

Clock behavior separates the two as well. The MI355X runs at a 1000 MHz base and 2400 MHz boost, while the RTX PRO 4000 Blackwell operates at a 1230 MHz base and 2055 MHz boost. The AMD chip has a higher boost clock but a lower base clock. Memory architecture is another major differentiator: the MI355X uses HBM3e with a 8192-bit bus, whereas the RTX PRO 4000 Blackwell uses GDDR7 with a 192-bit bus. The former is clearly designed for massive bandwidth, while the latter balances capacity and speed for workstation tasks.

# Head-to-Head Benchmarks

The head-to-head benchmark table in the database contains no entries, meaning there are no direct comparative scores recorded between the AMD Instinct MI355X and the NVIDIA RTX PRO 4000 Blackwell. The wins count reflects this: 0 wins for the AMD part and 0 wins for the NVIDIA part. Consequently, any comparison must rely on the individual data fields and the NVIDIA card's benchmark records.

For the RTX PRO 4000 Blackwell, the database lists nine benchmark results. In 3DMark Steel Nomad DX12, it scores 4648. Its Geekbench Vulkan score is 194168. PassMark results include 173 for DirectX 10, 276 for DirectX 11, 97 for DirectX 12, 354 for DirectX 9, 1265 for G2D, 28427 for G3D, and 14805 for GPU Compute. These scores place the card at the 72nd percentile among all GPUs in the database, with an average score of 27135.

The AMD Instinct MI355X has no benchmark scores recorded, a percentile ranking of 50, and an average benchmark score of 0. This absence of data means the MI355X cannot be positioned against the RTX PRO 4000 Blackwell through measured results. Instead, the comparison must be inferred from architectural and specification differences.

The nearest rivals for the RTX PRO 4000 Blackwell provide context for its performance tier. It sits within 1.7% of several cards: 1.1% below the RX 6700 XT and RTX 4070 Mobile, 1.6% below the RTX 3090, and 1.7% above the RTX A4000. These deltas indicate that the RTX PRO 4000 Blackwell performs in the same general class as those GPUs, though the exact workload distribution is not specified in the database.

# Specification Differences

The two cards differ across nearly every measurable specification field. The process node is 3 nm for the AMD part versus 5 nm for the NVIDIA part. Transistor count is 185,000 million for the MI355X against 45,600 million for the RTX PRO 4000 Blackwell. Die size is 2380 mm² versus 378 mm². Transistor density is 77.7M per mm² versus 120.6M per mm².

Clock speeds diverge: the MI355X has a 1000 MHz base and 2400 MHz boost, while the RTX PRO 4000 Blackwell has a 1230 MHz base and 2055 MHz boost. Memory clocks are listed as 2000 MHz (8 Gbps effective) for the AMD card and 1750 MHz (28 Gbps effective) for the NVIDIA card.

Memory capacity is 288 GB of HBM3e versus 24 GB of GDDR7. Bus width is 8192 bit versus 192 bit. Bandwidth is 8.19 TB/s versus 672.0 GB/s. Shading units are 16,384 versus 8,960. TMUs are 1,024 versus 280. ROPs are 0 versus 96. The RTX PRO 4000 Blackwell has 70 RT cores and 280 tensor cores; the MI355X has no such counts listed.

Pixel rate is 0 MPixel/s for the AMD part versus 197.3 GPixel/s for the NVIDIA part. Texture rate is 2,457.6 GTexel/s versus 575.4 GTexel/s. FP32 compute is 78.64 TFLOPS for the MI355X versus 36.83 TFLOPS for the RTX PRO 4000 Blackwell. FP16 is 78.64 TFLOPS (1:1) for both, but the AMD card's FP16 equals its FP32, while the NVIDIA card's FP16 also equals its FP32.

Power draw is the most extreme difference: the MI355X has a TDP of 1400 W with a suggested PSU of 1800 W, while the RTX PRO 4000 Blackwell has a TDP of 140 W and a suggested PSU of 300 W. The AMD card is an OAM module with no power connectors listed, whereas the NVIDIA card is a single-slot design with one 16-pin connector. The MI355X has no display outputs; the NVIDIA card has 4x DisplayPort 2.1b outputs. Physical dimensions are 102 mm by 165 mm for the AMD module versus 241 mm by 111 mm by 20 mm for the NVIDIA card. The NVIDIA card has an active production status, while the AMD card's status is not listed. Release dates are 2025-06-11 for the AMD part and 2025-03-17 for the NVIDIA part.

# Where Each One Wins

The AMD Instinct MI355X wins in raw compute throughput. Its FP32 performance of 78.64 TFLOPS is more than double the 36.83 TFLOPS of the RTX PRO 4000 Blackwell. Its texture rate of 2,457.6 GTexel/s exceeds the NVIDIA card's 575.4 GTexel/s by a wide margin. Memory bandwidth is overwhelmingly in the AMD card's favor: 8.19 TB/s versus 672.0 GB/s, enabled by the 8192-bit bus and 288 GB of HBM3e. For workloads that depend on massive data movement and dense FP32 or FP16 math, such as large-scale training or scientific simulation, the MI355X provides the higher ceiling.

The NVIDIA RTX PRO 4000 Blackwell wins in graphics and workstation versatility. It has a full rendering pipeline with 96 ROPs, 70 RT cores, and 280 tensor cores, plus support for DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4. Its pixel rate is 197.3 GPixel/s, while the AMD card delivers 0 MPixel/s. The NVIDIA card also has 4x DisplayPort 2.1b outputs, enabling direct display connectivity, which the AMD module lacks entirely. Its power envelope is far lower at 140 W versus 1400 W, and its physical form factor as a single-slot PCIe 5.0 x16 card with a 16-pin connector makes it deployable in standard workstations, whereas the AMD part requires an OAM module infrastructure.

The NVIDIA card also holds the only benchmark results in the database. It records a G3D score of 28427 and a GPU Compute score of 14805, along with a Geekbench Vulkan score of 194168. Its 72nd percentile ranking among all GPUs indicates solid performance relative to the broader database, while the AMD card's 50th percentile is based on no measured scores.

# The Verdict

The data presents a clear split. The AMD Instinct MI355X is a high-power, compute-only accelerator with no graphics output, no rendering hardware, and no benchmark entries. Its strengths are entirely in theoretical compute and memory bandwidth: 78.64 TFLOPS FP32, 8.19 TB/s bandwidth, and 288 GB of HBM3e capacity. It targets environments where raw arithmetic throughput and massive memory pools matter, and where the 1400 W power draw and OAM form factor are acceptable. The lack of any recorded benchmark scores, however, means its real-world performance cannot be validated from the database.

The NVIDIA RTX PRO 4000 Blackwell is a lower-power, fully featured workstation GPU. It offers a complete graphics stack, including RT and tensor cores, display outputs, and API support. Its 140 W TDP and single-slot size make it practical for conventional systems. The recorded benchmark scores show it performing near the RTX 3090, RX 6700 XT, and RTX 4070 Mobile, with deltas under 1.7% in all cases. Its percentile ranking of 72 places it above the median GPU in the database.

For users choosing between these two, the decision rests on workload type. The MI355X is the only option for tasks requiring its level of FP32 throughput, memory bandwidth, and capacity, provided the infrastructure can handle its power and module requirements. The RTX PRO 4000 Blackwell is the only option for tasks requiring graphics rendering, display output, or standard PCIe installation, and it has the advantage of verified benchmark results. The database does not support a direct performance comparison, as the head-to-head table is empty and the AMD card has no scores. Each product wins in its respective domain: the MI355X in raw compute scale, the RTX PRO 4000 Blackwell in measured, versatile workstation performance.