AMD Instinct MI300 vs NVIDIA RTX PRO 6000 Blackwell Server Comparison

Head-to-Head Benchmarks

The recorded data for the AMD Instinct MI300 contains no benchmark entries, while the NVIDIA RTX PRO 6000 Blackwell Server holds a single 3DMark Steel Nomad DX12 score of 5996. This asymmetry means a direct head-to-head comparison in the database is limited to the NVIDIA part’s measured result. The AMD Instinct MI300 shows an average benchmark score of 0 and zero recorded wins in any head-to-head test, while the NVIDIA card likewise has zero wins in the database’s head-to-head section, simply because no shared tests exist between the two products.

The NVIDIA RTX PRO 6000 Blackwell Server’s single benchmark score of 5996 places it at the 34th percentile among all GPUs in the database. Its nearest rivals in the recorded data are strikingly close: the NVIDIA GeForce GTX 770M scores 6000, a delta of -0.1 percent, the AMD Radeon RX 6400 also scores 6001, a delta of -0.1 percent, the AMD FirePro W4100 scores 5987, a delta of 0.2 percent, and the NVIDIA Quadro K4000M scores 5986, a delta of 0.2 percent. These deltas are all within a fraction of a percent, indicating that the RTX PRO 6000 Blackwell Server’s Steel Nomad result sits in a cluster of legacy and low-end parts in the database, despite its position as a top-tier server accelerator.

The AMD Instinct MI300, by contrast, has no benchmark scores and therefore no percentile rank beyond the neutral 50th percentile placeholder assigned to products without recorded measurements. The absence of data does not imply equivalence or inferiority; it simply reflects that the database has not recorded any synthetic benchmark runs for the MI300. The NVIDIA card’s percentile of 34 is derived solely from its one Steel Nomad score, which is an unusual metric for a compute-focused server GPU, as 3DMark Steel Nomad is a gaming-oriented DirectX 12 test. The MI300’s architecture, CDNA 3.0, is designed for data center compute rather than graphics workloads, which explains why no such benchmark appears in its profile.

The Verdict

Based solely on the recorded data, the NVIDIA RTX PRO 6000 Blackwell Server is the only product with a measurable benchmark result, and that result is 5996 in 3DMark Steel Nomad DX12. The AMD Instinct MI300 has no recorded benchmarks, so any selection between the two must rely on specification differences rather than performance scores. The database shows the RTX PRO 6000 Blackwell Server at the 34th percentile, with its nearest rivals within 0.2 percent of its score, which suggests that its Steel Nomad performance is comparable to much older or lower-tier GPUs in that specific test. However, this metric is not representative of the compute workloads for which either product is intended.

For users prioritizing a recorded benchmark result, the NVIDIA card is the only option with data. For users prioritizing raw compute specifications, the AMD Instinct MI300 offers more memory, 128 GB versus 96 GB, a wider memory bus, 8192 bit versus 512 bit, and significantly higher memory bandwidth, 5.32 TB/s versus 1.79 TB/s. The MI300 also has a larger transistor count of 153,000 million versus 92,200 million and a larger die size of 1017 mm² versus 750 mm². The NVIDIA card counters with higher clock speeds, a boost of 2617 MHz versus 1700 MHz, more shading units at 24064 versus 14080, and higher FP32 throughput at 126.0 TFLOPS versus 47.87 TFLOPS.

The verdict from the data is straightforward: the NVIDIA RTX PRO 6000 Blackwell Server has a verified benchmark score, while the AMD Instinct MI300 does not. Neither product shows a head-to-head win in the database because no shared tests exist. The choice depends on whether the user values the recorded graphics benchmark or the specification advantages in memory capacity and bandwidth.

Where Each One Wins

The AMD Instinct MI300 wins on memory capacity, offering 128 GB of HBM3 compared to the NVIDIA card’s 96 GB of GDDR7. The MI300’s memory bus width of 8192 bit is sixteen times wider than the NVIDIA card’s 512 bit, and its memory bandwidth of 5.32 TB/s is nearly three times the NVIDIA card’s 1.79 TB/s. These specifications indicate a design optimized for large data sets and memory-bound compute workloads, such as training large machine learning models or processing high-resolution scientific simulations. The MI300 also leads in transistor count, 153,000 million versus 92,200 million, and die size, 1017 mm² versus 750 mm², which reflects a more complex and physically larger silicon implementation.

The NVIDIA RTX PRO 6000 Blackwell Server wins on raw compute throughput per the recorded specifications. Its FP32 performance of 126.0 TFLOPS is more than double the MI300’s 47.87 TFLOPS, and its FP16 performance matches at 126.0 TFLOPS versus 47.87 TFLOPS. The NVIDIA card has more shading units, 24064 versus 14080, more texture mapping units, 752 versus 880 is actually a loss, but the NVIDIA card’s texture rate of 1,968.0 GTexel/s exceeds the MI300’s 1,496.0 GTexel/s. The NVIDIA card also includes 188 ray tracing cores and 752 tensor cores, while the MI300 lists no RT or tensor core counts. The NVIDIA card has a pixel rate of 502.5 GPixel/s, whereas the MI300 shows 0 MPixel/s, indicating no rasterization hardware. The NVIDIA card supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, while the MI300 lists N/A for all graphics APIs.

The NVIDIA card wins on clock speeds, with a base of 1590 MHz and boost of 2617 MHz versus the MI300’s 1000 MHz base and 1700 MHz boost. The NVIDIA card also has a higher memory clock at 1750 MHz 28 Gbps effective versus the MI300’s 1300 MHz 5.2 Gbps effective. The NVIDIA card is dual-slot with a 40 mm width, while the MI300’s slot width is not recorded. The NVIDIA card includes 4x DisplayPort 2.1b outputs, while the MI300 has no display outputs.

FAQ

Q: What is the recorded benchmark score for the AMD Instinct MI300?

A: The database contains no benchmark scores for the AMD Instinct MI300. Its average benchmark score is listed as 0, and its percentile versus all GPUs is set to 50 as a neutral placeholder.

Q: What is the recorded benchmark score for the NVIDIA RTX PRO 6000 Blackwell Server?

A: The NVIDIA RTX PRO 6000 Blackwell Server has a single recorded benchmark score of 5996 in the 3dmark_3dmark_steel_nomad_dx12 test. Its average benchmark score is also 5996.

Q: How does the NVIDIA RTX PRO 6000 Blackwell Server compare to its nearest rivals in the database?

A: Its nearest rivals are the NVIDIA GeForce GTX 770M with a score of 6000 and a delta of -0.1 percent, the AMD Radeon RX 6400 with a score of 6001 and a delta of -0.1 percent, the AMD FirePro W4100 with a score of 5987 and a delta of 0.2 percent, and the NVIDIA Quadro K4000M with a score of 5986 and a delta of 0.2 percent.

Q: Which product has more memory capacity?

A: The AMD Instinct MI300 has 128 GB of HBM3 memory, while the NVIDIA RTX PRO 6000 Blackwell Server has 96 GB of GDDR7 memory.

Q: Which product has higher FP32 throughput?

A: The NVIDIA RTX PRO 6000 Blackwell Server has FP32 throughput of 126.0 TFLOPS, while the AMD Instinct MI300 has FP32 throughput of 47.87 TFLOPS.

Q: Which product supports graphics APIs?

A: The NVIDIA RTX PRO 6000 Blackwell Server supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The AMD Instinct MI300 lists N/A for DirectX, OpenGL, and Vulkan.

Architecture Differences

The AMD Instinct MI300 uses the Aqua Vanjaram chip built on CDNA 3.0 architecture, manufactured by TSMC on a 5 nm process. The NVIDIA RTX PRO 6000 Blackwell Server uses the GB202 chip built on Blackwell 2.0 architecture, also manufactured by TSMC on a 5 nm process. Both products share the same process node and foundry, but their architectures diverge significantly in design philosophy.

The MI300 packages 153,000 million transistors on a 1017 mm² die, yielding a transistor density of 150.4 million per square millimeter. The NVIDIA card packages 92,200 million transistors on a 750 mm² die, yielding a density of 122.9 million per square millimeter. The MI300’s higher density and larger die indicate a more transistor-heavy design, likely due to its massive HBM3 memory interface and compute arrays.

The MI300 has 14080 shading units, 880 texture mapping units, and no ROPs, with a pixel rate of 0 MPixel/s. It has no recorded ray tracing cores or tensor cores. Its texture rate is 1,496.0 GTexel/s. The NVIDIA card has 24064 shading units, 752 texture mapping units, 192 ROPs, 188 ray tracing cores, and 752 tensor cores. Its pixel rate is 502.5 GPixel/s, and its texture rate is 1,968.0 GTexel/s. The presence of ROPs, RT cores, and tensor cores on the NVIDIA card confirms a graphics-capable design, while the MI300’s zero pixel rate and lack of RT/tensor core entries confirm a pure compute accelerator.

The NVIDIA card’s memory type, GDDR7, differs fundamentally from the MI300’s HBM3. The NVIDIA card uses a 512 bit bus with 1.79 TB/s bandwidth, while the MI300 uses an 8192 bit bus with 5.32 TB/s bandwidth. The MI300’s HBM3 stack enables far higher bandwidth at the cost of a much wider physical interface.

Specification Differences

Clock speeds differ substantially. The AMD Instinct MI300 has a base clock of 1000 MHz and a boost clock of 1700 MHz. The NVIDIA RTX PRO 6000 Blackwell Server has a base clock of 1590 MHz and a boost clock of 2617 MHz. The memory clock also differs: the MI300 runs at 1300 MHz with 5.2 Gbps effective, while the NVIDIA card runs at 1750 MHz with 28 Gbps effective.

Memory configuration differs in every field. The MI300 has 128 GB of HBM3 on an 8192 bit bus with 5.32 TB/s bandwidth. The NVIDIA card has 96 GB of GDDR7 on a 512 bit bus with 1.79 TB/s bandwidth.

Compute throughput differs sharply. The MI300 delivers 47.87 TFLOPS for both FP32 and FP16 (1:1). The NVIDIA card delivers 126.0 TFLOPS for both FP32 and FP16 (1:1).

Power and cooling specifications are identical in total power: both have a TDP of 600 W and a suggested PSU of 1000 W. The power connectors differ, with the MI300 using 2x 8-pin and the NVIDIA card using 1x 16-pin. The bus interface is PCIe 5.0 x16 for both. The NVIDIA card is dual-slot with a width of 40 mm, while the MI300’s slot width is not recorded. Both cards have identical dimensions in length, 267 mm or 10.5 inches, and height, 111 mm or 4.4 inches.

Display outputs differ completely. The MI300 has no outputs, while the NVIDIA card has 4x DisplayPort 2.1b. The NVIDIA card supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, while the MI300 lists N/A for all three APIs.

Release dates differ by over two years. The MI300 was released on 2023-01-03, while the NVIDIA card was released on 2025-03-17. The NVIDIA card’s production status is recorded as Active, while the MI300’s production status is not recorded. The NVIDIA card’s predecessor is listed as Server Hopper and its successor as Server Rubin, while the MI300’s predecessor is Radeon Instinct and its successor is not recorded. Neither product has a recorded launch MSRP.