AMD Instinct MI300 vs NVIDIA GeForce RTX 4080 SUPER Comparison

The Verdict

The database comparison between the AMD Instinct MI300 and the NVIDIA GeForce RTX 4080 SUPER is not a contest between equals; it is a study in divergent design goals. The MI300 is an accelerator with no display outputs, no graphics API support, and a 50th percentile ranking among all GPUs. The RTX 4080 SUPER is a consumer graphics card with full DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4 support, sitting at the 86th percentile. The data shows the RTX 4080 SUPER is the only one of the two that can render graphics, output video, or run gaming workloads. The MI300, with 128 GB of HBM3 memory and a 5.32 TB/s memory bandwidth, is built for compute tasks that demand enormous memory capacity. The verdict from the recorded measurements is straightforward: the RTX 4080 SUPER is for interactive graphics and general GPU workloads, while the MI300 is a specialized compute accelerator with no consumer-facing capabilities.

Where Each One Wins

The RTX 4080 SUPER wins in every measurable benchmark category because the MI300 has no benchmark entries in the database. The MI300's avgBenchmarkScore is 0, its benchmarks array is empty, and its winsA count is 0. The RTX 4080 SUPER's winsB count is also 0, but it has actual scores. Its PassMark G3D score is 34,245, its GeekBench Vulkan score is 260,075, and its GeekBench OpenCL score is 219,065. The RTX 4080 SUPER also records a 3DMark Steel Nomad DX12 score of 6,600. The MI300 produces no such numbers, so the use-case split is absolute: any workload that requires a score in the database belongs to the RTX 4080 SUPER. The MI300's strengths are architectural, not measured: 153,000 million transistors, a 1017 mm² die, and 8192-bit memory bus. Those specifications target server-scale compute, not desktop benchmarks.

Architecture Differences

The two chips share a 5 nm TSMC process node but diverge from there. The MI300 uses the CDNA 3.0 architecture on the Aqua Vanjaram chip, while the RTX 4080 SUPER uses Ada Lovelace on the AD103 chip. Transistor counts differ by a factor of more than three: the MI300 packs 153,000 million transistors on a 1017 mm² die, giving a density of 150.4M transistors per mm². The RTX 4080 SUPER has 45,900 million transistors on a 379 mm² die, with a density of 121.1M per mm². The MI300 has no ROPs, no RT cores, and no tensor cores listed, and its pixel rate is 0 MPixel/s. The RTX 4080 SUPER has 112 ROPs, 80 RT cores, and 320 tensor cores, with a pixel rate of 285.6 GPixel/s. The MI300 has 14,080 shading units and 880 TMUs, versus 10,240 shading units and 320 TMUs on the RTX 4080 SUPER. The MI300's texture rate is 1,496.0 GTexel/s, nearly double the RTX 4080 SUPER's 816.0 GTexel/s. The MI300's FP32 and FP16 both measure 47.87 TFLOPS, while the RTX 4080 SUPER reaches 52.22 TFLOPS in both. The MI300 is a compute accelerator with no graphics APIs, no display outputs, and no DirectX, OpenGL, or Vulkan support. The RTX 4080 SUPER supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, and outputs video through 1x HDMI 2.1 and 3x DisplayPort 1.4a.

FAQ

Q: Which card has more memory bandwidth?

A: The MI300 has 5.32 TB/s of memory bandwidth across a 8192-bit bus, while the RTX 4080 SUPER has 736.3 GB/s across a 256-bit bus.

Q: Can the MI300 output video to a display?

A: No. The database lists its display outputs as "No outputs," and its DirectX, OpenGL, and Vulkan APIs are all marked N/A.

Q: What is the RTX 4080 SUPER's average benchmark score relative to its nearest rivals?

A: Its avgBenchmarkScore is 54,209. It trails the NVIDIA GeForce RTX 4080 by 0.1%, the AMD Radeon Pro W5700X by 1.1%, the AMD Radeon RX 6750 GRE 12 GB by 2.7%, and the AMD Radeon 8060S by 2.8%.

Q: How do the power requirements compare?

A: The MI300 has a 600 W TDP with 2x 8-pin power connectors and a suggested PSU of 1000 W. The RTX 4080 SUPER has a 320 W TDP with 1x 16-pin connector and a suggested PSU of 700 W.

Q: Which card has more texture mapping units?

A: The MI300 has 880 TMUs, compared to the RTX 4080 SUPER's 320 TMUs, resulting in a texture rate of 1,496.0 GTexel/s versus 816.0 GTexel/s.

Q: What is the release timeline for these two products?

A: The MI300 was released on January 3, 2023, while the RTX 4080 SUPER was released on January 30, 2024, and its production status is listed as end-of-life.

Head-to-Head Benchmarks

No head-to-head benchmark entries exist in the database, and the MI300 has zero recorded benchmark scores. The comparison therefore relies on the RTX 4080 SUPER's measured performance and the MI300's architectural specifications. The RTX 4080 SUPER's PassMark G3D score of 34,245 and its PassMark GPU Compute score of 19,822 demonstrate measurable graphics and compute output. Its GeekBench OpenCL score of 219,065 and GeekBench Vulkan score of 260,075 show strong general-purpose and graphics-API performance. The 3DMark Steel Nomad DX12 score of 6,600 confirms modern DirectX 12 rendering capability. The MI300 cannot participate in any of these tests because it lacks the required APIs and display outputs. The nearest rival data for the RTX 4080 SUPER places it in a tight cluster: it is 0.1% behind the RTX 4080, 1.1% behind the Radeon Pro W5700X, 2.7% behind the Radeon RX 6750 GRE 12 GB, and 2.8% behind the Radeon 8060S. Those deltas are small, indicating that the RTX 4080 SUPER performs within a narrow band of its immediate competitors. The MI300 has no such comparison data, which reinforces its position as a non-benchmarked compute product in this database.

Specification Differences

The MI300 and RTX 4080 SUPER differ in nearly every measurable specification. The MI300 has 153,000 million transistors on a 1017 mm² die, while the RTX 4080 SUPER has 45,900 million on 379 mm². Transistor density is 150.4M per mm² for the MI300 and 121.1M per mm² for the RTX 4080 SUPER. Clock speeds: the MI300 runs at a base of 1000 MHz and a boost of 1700 MHz, with memory at 1300 MHz (5.2 Gbps effective). The RTX 4080 SUPER runs at a base of 2295 MHz and a boost of 2550 MHz, with memory at 1438 MHz (23 Gbps effective). Memory capacity is 128 GB of HBM3 for the MI300 versus 16 GB of GDDR6X for the RTX 4080 SUPER. Memory bus width is 8192 bit versus 256 bit, and bandwidth is 5.32 TB/s versus 736.3 GB/s. Shading units: 14,080 on the MI300 versus 10,240 on the RTX 4080 SUPER. TMUs: 880 versus 320. ROPs: 0 on the MI300 versus 112 on the RTX 4080 SUPER. RT cores: none listed on the MI300 versus 80 on the RTX 4080 SUPER. Tensor cores: none listed on the MI300 versus 320 on the RTX 4080 SUPER. Pixel rate is 0 MPixel/s on the MI300 versus 285.6 GPixel/s on the RTX 4080 SUPER. Texture rate is 1,496.0 GTexel/s versus 816.0 GTexel/s. FP32 and FP16 are 47.87 TFLOPS on the MI300 versus 52.22 TFLOPS on the RTX 4080 SUPER. TDP is 600 W versus 320 W. Power connectors are 2x 8-pin versus 1x 16-pin, and suggested PSU is 1000 W versus 700 W. Bus interface is PCIe 5.0 x16 versus PCIe 4.0 x16. Display outputs are none versus 1x HDMI 2.1 and 3x DisplayPort 1.4a. API support is N/A versus DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. Dimensions: the MI300 is 267 mm long and 111 mm tall, while the RTX 4080 SUPER is 310 mm long, 140 mm tall, and 61 mm wide, with a triple-slot form factor. The MI300 has no launch MSRP, while the RTX 4080 SUPER has a launch MSRP of 999 USD. The MI300's predecessor is Radeon Instinct, and the RTX 4080 SUPER's predecessor is GeForce 30, with its successor listed as GeForce 50. The MI300's percentile is 50, while the RTX 4080 SUPER's percentile is 86. The MI300's avgBenchmarkScore is 0, while the RTX 4080 SUPER's is 54,209. These differences confirm that the MI300 and RTX 4080 SUPER occupy entirely separate product categories, with no overlap in target workload, feature set, or measured performance.