AMD Ryzen 3 PRO 4355GE vs Intel Xeon E5-2643 v3 Comparison

Head-to-Head Benchmarks

The benchmark data from the database shows a clean sweep for the AMD Ryzen 3 PRO 4355GE across all six Cinebench tests, though the margins are surprisingly narrow given the architectural gulf between these two processors. The largest single win comes in Cinebench R20 single-core, where the AMD part leads by 3.5%, scoring 532 against Intel’s 514. Every other test falls within a tight 3.3% to 3.4% band, indicating that the Ryzen’s advantage is consistent rather than workload-specific.

In multi-threaded workloads, the Ryzen 3 PRO 4355GE posts 904 in Cinebench R15 multicore versus 875 for the Xeon E5-2643 v3, a 3.3% edge. That gap widens slightly in Cinebench R20 multicore, where the AMD chip scores 3769 against 3646, a 3.4% difference. The Cinebench R23 multicore result follows the same pattern: 8975 for AMD, 8682 for Intel, again a 3.4% margin. What makes these numbers notable is that the Intel Xeon carries two additional physical cores and four additional threads, yet still trails in every multi-threaded test.

Single-core results reinforce the same story. The Ryzen 3 PRO 4355GE scores 127 in Cinebench R15 single-core, while the Xeon manages 123, a 3.3% lead. In Cinebench R20 single-core, the gap grows to 3.5%, the widest margin recorded in this head-to-head. Cinebench R23 single-core shows 1267 for AMD against 1225 for Intel, a 3.4% advantage. The consistency of these deltas suggests that the Zen 2 architecture delivers superior per-thread performance across the board, regardless of the Cinebench version.

Looking at the broader database context, the Ryzen 3 PRO 4355GE holds an average benchmark score of 2596, placing it in the 49th percentile of all CPUs. Its nearest rival, the Intel Core i7-8850H, sits just 0.3% behind at 2604. The Intel Xeon E5-2643 v3, by comparison, averages 2511, also in the 49th percentile, with its closest competitor being the Intel Xeon E-2144G at 2514, a 0.1% gap. While both processors land in the same percentile tier, the AMD chip’s average score is roughly 3.4% higher, which aligns with the head-to-head deltas observed in the Cinebench suite.

Architecture Differences

The fundamental architectural split between these two chips explains much of the performance picture. The AMD Ryzen 3 PRO 4355GE is built on TSMC’s 7 nm process, while the Intel Xeon E5-2643 v3 uses Intel’s 22 nm node. That process advantage translates into dramatically different transistor densities: AMD packs 9,800 million transistors into a 156 mm² die, whereas Intel fits just 2,600 million transistors into a much larger 356 mm² die. The AMD part is a Zen 2 design from the Renoir codename family, part of the 4000 series, while Intel’s chip is Haswell-EP architecture from the Xeon E5 family.

Core counts also differ significantly. The Ryzen 3 PRO 4355GE offers 4 cores and 8 threads, while the Xeon E5-2643 v3 provides 6 cores and 12 threads. Despite having fewer cores, the AMD chip still wins every benchmark, which points to substantial per-core efficiency gains from the newer microarchitecture. Cache configurations reflect the generational divide. Both share 64 KB of L1 cache per core, but the AMD chip uses 512 KB of L2 per core versus Intel’s 256 KB. The L3 situation is reversed: Intel offers 20 MB shared, while AMD provides just 4 MB shared. That large L3 deficit does not appear to hurt AMD in the Cinebench tests recorded.

Memory subsystems differ as well. The Ryzen 3 PRO 4355GE runs dual-channel DDR4 with 51.2 GB/s of bandwidth, while the Xeon E5-2643 v3 uses quad-channel DDR4 and reaches 68.3 GB/s. Both support ECC memory, which is notable for a desktop-class AMD part. PCIe lanes also favor Intel: the Xeon provides 40 Gen 3 lanes from the CPU, while AMD offers only 16 Gen 3 lanes. The Ryzen includes integrated Radeon Vega 6 graphics, whereas the Xeon has no integrated GPU, requiring a discrete graphics card for any display output.

Clock speeds are close but favor AMD. The Ryzen 3 PRO 4355GE has a 3.50 GHz base clock and 4.00 GHz boost, while the Xeon E5-2643 v3 starts at 3.40 GHz and boosts to 3.70 GHz. Power consumption, however, is a stark differentiator. The AMD chip has a 35 W TDP, while the Intel part draws 135 W, making the Ryzen far more power-efficient on paper. The Xeon targets the server and workstation market and has reached end-of-life status, while the Ryzen remains active in the desktop segment. The Xeon launched with a launch MSRP of $1552, while the Ryzen has no recorded launch MSRP in the database.

The Verdict

The benchmark data clearly favors the AMD Ryzen 3 PRO 4355GE for workloads that rely on Cinebench-style rendering performance. It wins all six recorded tests, with margins between 3.3% and 3.5%, despite having two fewer cores and four fewer threads than the Intel Xeon E5-2643 v3. Users who prioritize single-threaded responsiveness will find the Ryzen’s 3.5% lead in Cinebench R20 single-core meaningful, especially for applications that scale poorly across cores.

The Intel Xeon E5-2643 v3 retains advantages that matter in specific contexts, even though it loses every benchmark in this comparison. Its quad-channel memory interface delivers 68.3 GB/s of bandwidth versus 51.2 GB/s for the Ryzen, which could benefit memory-intensive workloads not captured in these Cinebench tests. The Xeon also offers 40 PCIe Gen 3 lanes, compared to 16 on the AMD part, making it more suitable for systems with multiple expansion cards or high-bandwidth storage arrays.

For buyers choosing between these two today, the production status is a significant factor. The Ryzen 3 PRO 4355GE is listed as active, while the Xeon E5-2643 v3 is end-of-life. The AMD chip’s 35 W TDP also makes it far easier to cool and power, which is relevant for compact desktop builds or low-noise systems. The Xeon’s 135 W TDP, combined with its server-class socket, suggests it belongs in a workstation chassis with robust cooling.

The data indicates that the Ryzen is the better choice for general desktop productivity, rendering tasks, and any workload where per-core efficiency outweighs raw core count. The Xeon remains defensible only for legacy server platforms that require its specific socket, quad-channel memory, or 40-lane PCIe topology. For everything else, the AMD part delivers superior performance with substantially lower power draw.

Specification Differences

| Specification | AMD Ryzen 3 PRO 4355GE | Intel Xeon E5-2643 v3 |

| --- | --- | --- |

| Cores | 4 | 6 |

| Threads | 8 | 12 |

| Base Clock | 3.50 GHz | 3.40 GHz |

| Boost Clock | 4.00 GHz | 3.70 GHz |

| TDP | 35 W | 135 W |

| Socket | AMD Socket AM4 | Intel Socket 2011-3 |

| Architecture | Zen 2 (Renoir) | Haswell (Haswell-EP) |

| Process Node | 7 nm (TSMC) | 22 nm (Intel) |

| Transistors | 9,800 million | 2,600 million |

| Die Size | 156 mm² | 356 mm² |

| L2 Cache | 512 KB per core | 256 KB per core |

| L3 Cache | 4 MB shared | 20 MB shared |

| Memory Bus | Dual-channel | Quad-channel |

| Memory Bandwidth | 51.2 GB/s | 68.3 GB/s |

| PCIe | Gen 3, 16 Lanes (CPU only) | Gen 3, 40 Lanes (CPU only) |

| Integrated Graphics | Radeon Vega 6 | None |

| Market Segment | Desktop | Server/Workstation |

| Production Status | Active | End-of-life |

| Release Date | 2022-11-10 | 2014-09-07 |

| Launch MSRP | None recorded | $1552 |

FAQ

Q: Which processor wins in Cinebench R23 multicore?

A: The AMD Ryzen 3 PRO 4355GE scores 8975, while the Intel Xeon E5-2643 v3 scores 8682, giving AMD a 3.4% advantage.

Q: Does the Intel Xeon have more cores than the AMD Ryzen?

A: Yes. The Xeon E5-2643 v3 has 6 cores and 12 threads, while the Ryzen 3 PRO 4355GE has 4 cores and 8 threads.

Q: Which CPU supports more memory bandwidth?

A: The Intel Xeon E5-2643 v3 offers 68.3 GB/s via quad-channel DDR4, while the AMD Ryzen 3 PRO 4355GE provides 51.2 GB/s through dual-channel DDR4.

Q: Is the AMD Ryzen 3 PRO 4355GE still in production?

A: Yes, the database lists it as active. The Intel Xeon E5-2643 v3 is listed as end-of-life.

Q: What is the TDP difference between these two processors?

A: The AMD Ryzen 3 PRO 4355GE has a 35 W TDP, while the Intel Xeon E5-2643 v3 has a 135 W TDP, a difference of 100 W.

Q: Which processor has integrated graphics?

A: Only the AMD Ryzen 3 PRO 4355GE includes integrated Radeon Vega 6 graphics. The Intel Xeon E5-2643 v3 has no integrated GPU.