AMD Ryzen 7 PRO 5750GE vs Intel Xeon E-2378G Comparison

The Verdict

The benchmark data presents an unusually consistent picture: the AMD Ryzen 7 PRO 5750GE wins every single head-to-head Cinebench test, but by margins so narrow that they border on statistical noise. The largest advantage is 1.7 percent in Cinebench R20 single-core, and the smallest is 1.5 percent in R15 single-core. Every other test lands at a 1.6 percent delta. This is not a processor that dominates its rival; it is one that edges ahead across the board while consuming dramatically less power.

For a server or workstation buyer, the Intel Xeon E-2378G remains a defensible choice because it offers the same core and thread count, a higher boost clock, and PCIe Gen 4 support, all within a platform designed for professional use. The data shows the Xeon trails by roughly 1.6 percent in every measured workload, a gap that will rarely be perceptible in real-world use. The AMD Ryzen 7 PRO 5750GE, however, delivers essentially equal performance at a 35 watt TDP compared to 80 watts, which is a substantial efficiency advantage that the benchmarks cannot directly express but the specifications clearly show.

The database places both processors at the 60th percentile among all CPUs, indicating they occupy the same performance tier. The Xeon's average benchmark score is 5199, while the Ryzen PRO's is 5070. That 129-point difference is curious because the Ryzen wins every Cinebench test, yet the Xeon has the higher average. The explanation lies in the benchmark mix: the Ryzen has two additional Geekbench results (6918 multicore, 1933 singlecore) that are not present for the Xeon, and those scores drag its average down relative to the Cinebench-only dataset for Intel. This is a reminder that average scores across different test suites should be interpreted with caution.

Architecture Differences

The two processors come from fundamentally different design philosophies. The Intel Xeon E-2378G is built on Rocket Lake-E, a 14 nm architecture manufactured at Intel's own foundry. The AMD Ryzen 7 PRO 5750GE uses Zen 3, codenamed Cezanne, fabricated on a 7 nm process at TSMC. That process node difference is the single most important architectural gap: AMD packs 10,700 million transistors into an 180 mm² die, while Intel's chip spans 276 mm². The transistor density advantage is enormous, and it explains how AMD achieves comparable performance at less than half the TDP.

Both processors have 8 cores and 16 threads, so thread scheduling and core topology are not differentiators. The cache hierarchy differs slightly: Intel provides 80 KB of L1 per core, while AMD provides 64 KB per core. Both have 512 KB of L2 per core and 16 MB of shared L3. The L3 arrangement is identical in capacity but the underlying architecture is different, with AMD's Zen 3 using a unified 16 MB pool accessible by all cores, while Intel's Rocket Lake uses a shared 16 MB design as well. The L1 difference favors Intel, but the benchmark results suggest it does not translate into a performance advantage.

The integrated graphics are a major architectural divergence. Intel pairs the Xeon with UHD Graphics P750, while AMD equips the Ryzen PRO with Radeon Vega 8. The database does not include graphics benchmarks, so a direct comparison is not possible from the recorded data, but the presence of two different iGPU designs means system integrators should evaluate their display output needs separately from CPU performance.

Memory support is identical in type (DDR4), channel configuration (dual-channel), and theoretical bandwidth (51.2 GB/s). Both support ECC memory, which is critical for the Xeon's server/workstation positioning and is a notable feature for the Ryzen PRO as well. The PCIe implementation differs: Intel offers Gen 4 with 20 lanes from the CPU, while AMD offers Gen 3 with 16 lanes. This is a meaningful advantage for the Xeon in storage and accelerator scenarios that can use the newer standard.

Head-to-Head Benchmarks

The Cinebench results form a remarkably tight cluster. In Cinebench R15 multicore, the Ryzen PRO scores 1841 against the Xeon's 1811, a 1.6 percent advantage. The single-core R15 test shows 259 versus 255, a 1.5 percent edge for AMD. Moving to R20, the multicore result is 7674 for AMD and 7549 for Intel, again a 1.6 percent gap. The R20 single-core test shows 1083 versus 1065, a 1.7 percent margin, the largest in the dataset. Cinebench R23 multicore scores 18272 for AMD and 17974 for Intel, a 1.6 percent difference, while R23 single-core lands at 2579 versus 2537, also 1.6 percent.

The consistency of these deltas is striking. Across six different rendering workloads, the AMD processor never varies beyond a 1.5 to 1.7 percent window. This suggests the two chips are thermally and power constrained in similar ways during these tests, despite the massive TDP gap. The Xeon's 5.10 GHz boost clock versus the Ryzen's 4.60 GHz does not overcome the architectural efficiency of Zen 3. The Ryzen's higher base clock of 3.20 GHz versus 2.80 GHz may contribute to its edge in shorter workloads, but the sustained multicore results show the advantage persists even as boost behavior comes into play.

For the Xeon, the nearest rival in the database is the Intel Core i5-13400T with an average score of 5210, a delta of negative 0.2 percent. The Xeon is also nearly tied with the Core i9-10850K (5240, negative 0.8 percent) and Core i7-11700B (5241, negative 0.8 percent). The Ryzen PRO's nearest rival is the Intel Xeon W-2155 at 5072, a zero percent delta, followed by the Core i9-12900TE (5050, 0.4 percent ahead of AMD) and Core i9-9820X (5049, 0.4 percent ahead). This places both chips in the same competitive neighborhood, with the Xeon marginally ahead in average score but behind in every direct Cinebench comparison.

Specification Differences

The two processors differ in several key specification fields. The base clock is 2.80 GHz for the Xeon and 3.20 GHz for the Ryzen PRO, an advantage of 0.40 GHz for AMD at idle-to-light loads. The boost clock is 5.10 GHz for Intel and 4.60 GHz for AMD, an advantage of 0.50 GHz for Intel under single-core boost conditions. The TDP is 80 watts for the Xeon and 35 watts for AMD, a 45 watt difference that is the most consequential specification gap.

The socket is Intel Socket 1200 for the Xeon and AMD Socket AM4 for the Ryzen PRO, meaning platform choice dictates which processor can be used. The process node is 14 nm for Intel and 7 nm for AMD, with TSMC as the foundry for the latter. The die size is 276 mm² for Intel and 180 mm² for AMD, and the transistor count is 10,700 million for AMD while the database records no figure for Intel. The L1 cache is 80 KB per core for Intel and 64 KB per core for AMD. The PCIe implementation is Gen 4 with 20 lanes for Intel and Gen 3 with 16 lanes for AMD. The integrated graphics are UHD Graphics P750 for Intel and Radeon Vega 8 for AMD. The market segment is Server/Workstation for Intel and Desktop for AMD. The release dates differ: September 2021 for Intel and May 2021 for AMD. The Xeon has a launch MSRP of $494, while the Ryzen PRO has no recorded launch MSRP. Both processors have locked multipliers and are still in active production.

FAQ

Q: Which processor is faster in multi-core rendering?

A: The AMD Ryzen 7 PRO 5750GE wins every multicore Cinebench test. In R23 multicore, it scores 18272 against the Xeon's 17974, a 1.6 percent advantage. The R20 multicore result is 7674 versus 7549, also a 1.6 percent gap.

Q: Does the Intel Xeon's higher boost clock give it a single-core advantage?

A: No. Despite boosting to 5.10 GHz versus the Ryzen's 4.60 GHz, the Xeon loses every single-core Cinebench test. The R23 single-core result is 2537 for Intel and 2579 for AMD, a 1.6 percent deficit for the Xeon.

Q: How do the TDP ratings compare?

A: The Intel Xeon E-2378G has an 80 watt TDP, while the AMD Ryzen 7 PRO 5750GE has a 35 watt TDP. The AMD processor delivers superior benchmark scores at less than half the thermal design power.

Q: Do both processors support ECC memory?

A: Yes, both the Xeon E-2378G and the Ryzen 7 PRO 5750GE support ECC memory. Both use dual-channel DDR4 with a theoretical bandwidth of 51.2 GB/s.

Q: What is the PCIe generation difference?

A: The Intel Xeon supports PCIe Gen 4 with 20 lanes from the CPU, while the AMD Ryzen PRO supports PCIe Gen 3 with 16 lanes. This gives the Xeon a bandwidth advantage for compatible devices.

Q: Which processor has a higher average benchmark score?

A: The Intel Xeon E-2378G has an average benchmark score of 5199, while the AMD Ryzen 7 PRO 5750GE has 5070. However, the AMD processor wins every direct head-to-head Cinebench test, and the average difference is influenced by the Ryzen's additional Geekbench results (6918 multicore, 1933 singlecore), which are not recorded for the Xeon.

Where Each One Wins

The AMD Ryzen 7 PRO 5750GE wins every measured benchmark in the head-to-head dataset. Its largest victory is 1.7 percent in Cinebench R20 single-core, and its smallest is 1.5 percent in R15 single-core. All other tests show a 1.6 percent margin. For workloads that resemble Cinebench rendering, whether single-threaded or multi-threaded, the data consistently favors AMD. The 35 watt TDP also makes it the superior choice for thermally constrained systems, dense deployments, or any scenario where power delivery and cooling are limited. The 7 nm process and 10,700 million transistors in an 180 mm² die explain how AMD achieves this efficiency.

The Intel Xeon E-2378G wins in areas that are not directly benchmarked but are clearly specified. PCIe Gen 4 with 20 lanes is a genuine advantage for systems using NVMe storage, GPUs, or accelerators that support the newer standard. The 80 KB per-core L1 cache is larger than AMD's 64 KB per-core allocation. The launch MSRP of $494 provides a reference point for procurement, though the database does not record a comparable price for the AMD part. The Xeon's 5.10 GHz boost clock, while not translating to Cinebench victories, may benefit workloads that are sensitive to maximum frequency in short bursts, though the recorded data does not show such an effect.

The market segment labels are instructive: Intel positions the E-2378G for server and workstation use, while AMD targets the Ryzen PRO 5750GE at desktop systems. Both support ECC memory, so the Xeon's professional positioning is not unique. For a buyer choosing between these two, the data suggests the Ryzen PRO offers identical or slightly better rendering performance with a fraction of the power draw, while the Xeon offers a newer PCIe standard and a higher boost clock on a platform with a longer server pedigree. The average score difference (5199 versus 5070) slightly favors Intel, but the head-to-head results favor AMD, and the specification sheet heavily favors AMD on efficiency. The decision ultimately comes down to platform requirements: Socket 1200 versus Socket AM4, PCIe Gen 4 versus Gen 3, and 80 watts versus 35 watts.