AMD Ryzen 7 PRO 5750G vs Intel Xeon E-2378 Comparison

The AMD Ryzen 7 PRO 5750G and Intel Xeon E-2378 are both 8-core, 16-thread processors aimed at professional desktop and workstation use, yet benchmark results reveal a fascinating split. The data shows each chip claims victory in different Cinebench versions, with the AMD part dominating the older R15 test while the Intel part takes a commanding lead in the newer R23 test, suggesting that workload characteristics and software optimization play a significant role in determining which processor is faster.

Head-to-Head Benchmarks

The head-to-head comparison presents a starkly divided picture. In Cinebench R15 multi-core, the AMD Ryzen 7 PRO 5750G scores 1956 against the Intel Xeon E-2378’s 1474, a 32.7% advantage. This is not a small margin; it indicates that in this particular legacy workload, the AMD chip is substantially faster at utilizing all 8 cores. The single-core R15 result follows a similar pattern, with AMD winning 241 to 208, a 15.9% lead. These are decisive wins for AMD.

However, the narrative flips dramatically when moving to Cinebench R23. The Intel Xeon E-2378 scores 14633 in multi-core, while the AMD Ryzen 7 PRO 5750G manages only 12157. This represents a 16.9% swing in Intel’s favor. The single-core R23 result is even more lopsided: Intel scores 2065 against AMD’s 1500, a 27.4% advantage. The shift from R15 to R23 is enormous — AMD goes from a 32.7% lead to a 16.9% deficit in multi-core, and from a 15.9% lead to a 27.4% deficit in single-core.

What explains this discrepancy? The R15 and R23 tests are both CPU-bound rendering benchmarks, but they scale differently with memory bandwidth, cache latency, and instruction-level parallelism. The AMD chip’s Zen 3 architecture excels in the older test, while Intel’s Rocket Lake architecture appears far better optimized for the newer workload. The data does not lie: these are two different performance profiles entirely dependent on which software generation is used. With 2 wins each, neither chip is universally superior, and the choice between them hinges on the specific Cinebench version — or more broadly, the software environment — a user targets.

Architecture Differences

The underlying hardware reveals why these benchmark patterns emerge. The AMD Ryzen 7 PRO 5750G is built on TSMC’s 7 nm process node, packing 10,700 million transistors into a 180 mm² die. In contrast, the Intel Xeon E-2378 uses Intel’s 14 nm process, with a 276 mm² die size and no transistor count listed. The process node difference is significant: 7 nm versus 14 nm means AMD has a two-generation advantage in transistor density and power efficiency, yet the Intel chip still wins R23 by a wide margin.

Both processors feature 8 cores and 16 threads, and both have 16 MB of L3 cache. However, the cache organization differs: AMD uses 16 MB as a unified pool, while Intel specifies it as shared. L1 cache also varies, with Intel offering 80 KB per core versus AMD’s 64 KB per core. L2 cache is identical at 512 KB per core. These cache differences could explain Intel’s R23 advantage, as larger per-core L1 cache reduces latency for frequently accessed data.

Memory support is similar — both support DDR4 with dual-channel memory and 51.2 GB/s bandwidth, and both support ECC memory. PCIe capabilities differ: Intel offers Gen 4 with 20 lanes (CPU only), while AMD provides Gen 3 with 16 lanes. This is a notable hardware advantage for Intel in terms of I/O bandwidth. The integrated graphics also differ: AMD includes Radeon Vega 8, while Intel has no integrated graphics at all. Socket compatibility separates them as well, with AMD using Socket AM4 and Intel using Socket 1200.

The process node disparity — 7 nm versus 14 nm — typically suggests the AMD part should be more efficient and faster, yet the R23 results contradict that expectation. This implies Intel’s Rocket Lake architecture, despite being on an older node, has superior IPC (instructions per clock) in certain workloads, or that AMD’s Cezanne design is optimized for a different balance of compute and memory access.

The Verdict

The data presents a clear but conditional verdict. For users running legacy or R15-era applications, the AMD Ryzen 7 PRO 5750G is the superior choice, delivering a 32.7% multi-core and 15.9% single-core performance advantage. Its 7 nm process, integrated graphics, and lower die size also suggest better power efficiency and system simplicity, especially for builds without a discrete GPU.

For users running modern R23-era workloads, the Intel Xeon E-2378 is unambiguously faster, with a 16.9% multi-core and 27.4% single-core lead. The Intel chip also offers PCIe Gen 4 support, double the lanes of AMD, making it better suited for high-bandwidth storage or accelerators. Its launch MSRP is $362, which is a data point for consideration, though pricing comparisons are not part of this analysis.

The average benchmark scores are close — AMD at 4296 and Intel at 4232 — with AMD holding a 1.5% edge. Both chips sit in the 57th to 58th percentile of all CPUs, indicating they are mid-tier performers. The nearest rivals for AMD include the Intel Xeon W-2140B (0.6% slower) and Intel Core i7-7820X (0.6% faster), while Intel’s rivals include the Core i5-12500T (0.4% slower) and Core i5-11500H (1.1% slower). Neither chip dominates its peer group.

FAQ

Q: Which processor is faster in Cinebench R23 multi-core?

A: The Intel Xeon E-2378, scoring 14633 against the AMD Ryzen 7 PRO 5750G’s 12157, a 16.9% advantage.

Q: Does the AMD Ryzen 7 PRO 5750G win any benchmarks?

A: Yes, it wins both Cinebench R15 tests: multi-core (1956 vs 1474, a 32.7% lead) and single-core (241 vs 208, a 15.9% lead).

Q: Do both processors support ECC memory?

A: Yes, both the AMD Ryzen 7 PRO 5750G and Intel Xeon E-2378 list ECC memory support as true.

Q: What is the process node difference between the two chips?

A: The AMD Ryzen 7 PRO 5750G uses a 7 nm process from TSMC, while the Intel Xeon E-2378 uses Intel’s 14 nm process.

Q: Does the Intel Xeon E-2378 have integrated graphics?

A: No, the Intel Xeon E-2378 has no integrated graphics, while the AMD Ryzen 7 PRO 5750G includes Radeon Vega 8.

Q: What is the single-core score gap in Cinebench R23?

A: The Intel Xeon E-2378 scores 2065 versus AMD’s 1500, giving Intel a 27.4% advantage.

Where Each One Wins

The AMD Ryzen 7 PRO 5750G wins decisively in Cinebench R15, both multi-core and single-core, with margins of 32.7% and 15.9% respectively. This suggests it is the better choice for older software, legacy rendering pipelines, or applications that have not been updated to leverage newer instruction sets. The AMD chip also has integrated Radeon Vega 8 graphics, which is a functional advantage for systems that require a display output without a dedicated GPU. Its 7 nm process node likely contributes to better thermal behavior and power efficiency, though no wattage figures are available beyond the 65 W TDP shared by both.

The Intel Xeon E-2378 wins in Cinebench R23, with a 16.9% multi-core and 27.4% single-core advantage. This makes it the superior option for modern workloads that are optimized for newer CPU architectures, such as recent video encoding, 3D rendering, or scientific computing applications. Intel’s PCIe Gen 4 support with 20 lanes is a significant I/O advantage over AMD’s PCIe Gen 3 with 16 lanes, enabling faster NVMe storage and high-bandwidth expansion cards. For server or workstation deployments where the latest software is standard, the Intel chip is the clear performance pick.

Specification Differences

The two processors differ in several key specifications. The AMD Ryzen 7 PRO 5750G has a base clock of 3.80 GHz and a boost clock of 4.60 GHz, while the Intel Xeon E-2378 has a base clock of 2.60 GHz and a boost clock of 4.80 GHz. Intel’s higher boost clock likely contributes to its R23 single-core dominance. Both have 8 cores and 16 threads, but the architecture differs: AMD uses Zen 3 with the Cezanne codename, while Intel uses Rocket Lake with the Rocket Lake-E codename.

Process nodes are distinct: AMD uses 7 nm from TSMC, while Intel uses 14 nm from its own foundry. The AMD die is 180 mm² with 10,700 million transistors, whereas the Intel die is 276 mm² with no transistor count listed. L1 cache differs (64 KB per core for AMD, 80 KB per core for Intel), while L2 and L3 are the same (512 KB per core and 16 MB, respectively). Memory support is identical in type (DDR4), bus (dual-channel), and bandwidth (51.2 GB/s), and both support ECC.

PCIe capability is a major difference: Intel provides Gen 4 with 20 lanes, while AMD provides Gen 3 with 16 lanes. Integrated graphics are present only on AMD (Radeon Vega 8); Intel has none. Sockets differ (AM4 vs LGA 1200), and the market segments differ (Desktop for AMD, Server/Workstation for Intel). Release dates are also different, with AMD launching on 2021-05-31 and Intel on 2021-09-07. The Intel part has a launch MSRP of $362, while AMD’s is not listed.