AMD Ryzen 5 PRO 4655G vs Intel Xeon E-2378 Comparison

Head-to-Head Benchmarks

The benchmark data presents a remarkably consistent picture. Across all six Cinebench tests, the Intel Xeon E-2378 takes the win, with no single test favoring the AMD Ryzen 5 PRO 4655G. The margins are tight but uniform, hovering around 5.5% in every workload.

Starting with multi-core performance, the Xeon E-2378 scores 1474 in Cinebench R15 multi-core, against 1397 for the Ryzen 5 PRO 4655G, a 5.5% advantage. Moving to Cinebench R20 multi-core, the Intel part scores 6145 versus 5823, again a 5.5% edge. In Cinebench R23 multi-core, the gap is identical in percentage terms: 14633 for the Xeon versus 13866 for the Ryzen, another 5.5% delta.

Single-core results tell the same story. In Cinebench R15 single-core, the Xeon E-2378 posts 208 points, while the Ryzen 5 PRO 4655G manages 197, a 5.6% lead. Cinebench R20 single-core shows 867 for Intel and 821 for AMD, also a 5.6% gap. Finally, Cinebench R23 single-core gives 2065 for the Xeon against 1957 for the Ryzen, a 5.5% difference.

The consistency of these deltas is noteworthy. Whether the workload is single-threaded or heavily multi-threaded, the Xeon E-2378 maintains the same relative advantage. This suggests the performance difference is structural rather than workload-specific. The average benchmark score reflects this: the Xeon E-2378 sits at 4232, while the Ryzen 5 PRO 4655G trails at 4010.

Context from the nearest rivals reinforces where each chip stands. The Xeon E-2378, with an average score of 4232, lands within 0.4% of the Intel Core i7-1265U (4248) and 0.9% behind the Intel Xeon W-2140B (4272). The Ryzen 5 PRO 4655G, at 4010, is essentially tied with the Intel Core i5-12400T (4019, a 0.2% delta) and the Intel Xeon E5-2698B v3 (4004, a 0.2% delta). Both processors occupy the 57th percentile among all CPUs, meaning they sit in the same broad performance tier, but the Intel Xeon E-2378 is consistently ahead within that tier.

Where Each One Wins

The data is unambiguous: the Intel Xeon E-2378 wins every benchmark in the comparison. There is no test where the AMD Ryzen 5 PRO 4655G comes out ahead, whether in single-core or multi-core workloads.

That said, the margins are small enough that the practical difference may not matter for every use case. A 5.5% multi-core lead in Cinebench R23 translates to roughly 767 points, which is measurable but not transformative. For heavily threaded rendering tasks, the Xeon E-2378 will finish slightly sooner, but the Ryzen 5 PRO 4655G is not far behind.

Where the Ryzen 5 PRO 4655G does have a distinct advantage is in platform characteristics rather than raw compute. It includes integrated Radeon Vega 7 graphics, which the Xeon E-2378 entirely lacks. For a system that needs a display output without a discrete GPU, the Ryzen part is the only option between these two. The Xeon E-2378 requires a separate graphics card, adding cost and complexity to any build that uses it.

The Ryzen 5 PRO 4655G also runs on a 7 nm process from TSMC, compared to the Xeon's 14 nm Intel process. This means the AMD chip has a smaller die (156 mm² versus 276 mm²) and fewer transistors overall (9,800 million versus no listed figure for Intel). However, both parts share the same 65 W TDP and the same dual-channel DDR4 memory bandwidth of 51.2 GB/s, so power and memory characteristics are equal.

For users who already have an AMD Socket AM4 motherboard, the Ryzen 5 PRO 4655G is the natural drop-in choice. Conversely, the Xeon E-2378 requires an Intel Socket 1200 platform. The socket difference is a major practical consideration that the benchmark scores alone do not capture.

The Verdict

Based strictly on the recorded data, the Intel Xeon E-2378 is the faster processor in every measured benchmark. It leads by 5.5% in multi-core tests and 5.5% to 5.6% in single-core tests. The average benchmark score of 4232 versus 4010 gives the Xeon a 5.5% overall edge. There is no scenario in the data where the Ryzen 5 PRO 4655G outperforms it.

However, the Xeon E-2378 is a server and workstation part, released in September 2021, and it carries a launch MSRP of $362. It has no integrated graphics, so any system built around it needs a discrete GPU. The Ryzen 5 PRO 4655G, released later in November 2022, is a desktop part with Radeon Vega 7 graphics built in. For a compact office PC, a home theater setup, or any build where a dedicated GPU is undesirable, the Ryzen part is the pragmatic choice despite its slightly lower scores.

For users who prioritize raw compute performance, especially in multi-threaded rendering or compilation workloads, the Xeon E-2378 is the clear pick. Its consistent 5.5% lead across all Cinebench versions indicates that the advantage holds regardless of workload intensity. The Xeon also supports PCIe Gen 4 with 20 CPU lanes, while the Ryzen is limited to PCIe Gen 3 with the same lane count, which matters for fast NVMe storage or newer GPUs.

For users who need an all-in-one solution with integrated graphics, or who are building on an existing AM4 platform, the Ryzen 5 PRO 4655G is the sensible option. The performance gap is small enough that most users will not notice it in everyday tasks, and the integrated GPU eliminates a significant component cost. Both processors sit at the 57th percentile among all CPUs, so neither is a high-end part; they are mid-range performers with similar overall capability.

FAQ

Q: Which processor is faster in multi-core workloads?

A: The Intel Xeon E-2378 wins all multi-core tests. In Cinebench R23 multi-core, it scores 14633 against 13866 for the AMD Ryzen 5 PRO 4655G, a 5.5% advantage. The same margin applies to Cinebench R15 (1474 versus 1397) and Cinebench R20 (6145 versus 5823).

Q: How do the single-core scores compare?

A: The Xeon E-2378 leads in every single-core test as well. Cinebench R23 single-core gives 2065 for Intel versus 1957 for AMD, a 5.5% gap. Cinebench R15 shows 208 versus 197 (5.6%), and Cinebench R20 shows 867 versus 821 (5.6%).

Q: Does the AMD Ryzen 5 PRO 4655G have integrated graphics?

A: Yes, it includes Radeon Vega 7 integrated graphics. The Intel Xeon E-2378 has no integrated graphics at all, so a discrete GPU is required for any display output with that processor.

Q: What are the core and thread counts for each?

A: The Intel Xeon E-2378 has 8 cores and 16 threads. The AMD Ryzen 5 PRO 4655G has 6 cores and 12 threads. Despite having fewer cores, the Ryzen stays within 5.5% in multi-core benchmarks.

Q: Do both support ECC memory?

A: Yes, both processors support ECC memory. They also both use dual-channel DDR4 with a memory bandwidth of 51.2 GB/s, so memory capabilities are identical.

Q: Which processor has a higher boost clock?

A: The Intel Xeon E-2378 boosts to 4.80 GHz, while the AMD Ryzen 5 PRO 4655G boosts to 4.20 GHz. The Xeon also has a lower base clock at 2.60 GHz versus 3.70 GHz for the Ryzen, but its higher boost accounts for the single-core performance lead.

Architecture Differences

The two processors come from fundamentally different design lineages. The Intel Xeon E-2378 is built on Rocket Lake architecture, specifically the Rocket Lake-E variant, using a 14 nm process at Intel's own foundry. It has a die size of 276 mm². The AMD Ryzen 5 PRO 4655G uses Zen 2 architecture with the Renoir codename, fabricated on a 7 nm process at TSMC, with a die size of 156 mm² and 9,800 million transistors.

Cache layouts differ noticeably. The Xeon E-2378 has 80 KB of L1 cache per core, 512 KB of L2 per core, and 16 MB of shared L3 cache. The Ryzen 5 PRO 4655G has 64 KB of L1 per core, 512 KB of L2 per core, and only 8 MB of shared L3 cache. The Xeon's larger L3 cache likely contributes to its consistent lead in single-core benchmarks.

The Xeon E-2378 supports PCIe Gen 4 with 20 CPU lanes, while the Ryzen 5 PRO 4655G is limited to PCIe Gen 3 with the same 20 lanes. This is a meaningful difference for storage and GPU bandwidth. The Xeon also carries a different market positioning: it is classified as a server and workstation part, while the Ryzen is a desktop processor. The Xeon includes integrated graphics? No, it does not. The Ryzen includes Radeon Vega 7, which is a significant architectural feature that the Intel part lacks entirely.

Both processors use the same dual-channel DDR4 memory interface with 51.2 GB/s bandwidth, and both support ECC memory. The Xeon E-2378 is part of the Xeon E-2300 series, released in September 2021, with a launch MSRP of $362. The Ryzen 5 PRO 4655G is part of the 4000 series, released in November 2022, with no launch MSRP listed in the database.

Specification Differences

| Specification | Intel Xeon E-2378 | AMD Ryzen 5 PRO 4655G |

|---|---|---|

| Cores | 8 | 6 |

| Threads | 16 | 12 |

| Base Clock | 2.60 GHz | 3.70 GHz |

| Boost Clock | 4.80 GHz | 4.20 GHz |

| Process Node | 14 nm | 7 nm |

| Foundry | Intel | TSMC |

| Die Size | 276 mm² | 156 mm² |

| Transistors | Not listed | 9,800 million |

| L1 Cache | 80 KB per core | 64 KB per core |

| L2 Cache | 512 KB per core | 512 KB per core |

| L3 Cache | 16 MB shared | 8 MB shared |

| Socket | Intel Socket 1200 | AMD Socket AM4 |

| PCIe | Gen 4, 20 Lanes | Gen 3, 20 Lanes |

| Integrated Graphics | None | Radeon Vega 7 |

| Market Segment | Server/Workstation | Desktop |

| Release Date | September 2021 | November 2022 |

| Launch MSRP | $362 | Not listed |

| Part Number | SRKN4 | 100-00001155, 100-00001155MPK |

Both processors share a 65 W TDP, dual-channel DDR4 memory support, 51.2 GB/s memory bandwidth, and ECC memory support. Neither has an unlocked multiplier. The Xeon E-2378 ranks at the 57th percentile among all CPUs with an average benchmark score of 4232, while the Ryzen 5 PRO 4655G also sits at the 57th percentile with an average score of 4010. The Xeon wins all six head-to-head benchmark comparisons.