AMD EPYC 7543P vs AMD Ryzen 5 4600H Comparison

The AMD EPYC 7543P and AMD Ryzen 5 4600H occupy opposite ends of the computing spectrum, yet the benchmark database places them within a fraction of a percent in average score. The EPYC 7543P, a 32-core server processor built on Zen 3, averages 16,395 points, while the Ryzen 5 4600H, a 6-core mobile chip on Zen 2, averages 16,341 points. The delta between them is a mere 0.3%, placing both at the 70th percentile among all CPUs. This statistical near-tie masks a fundamental divergence in workload behavior, where the EPYC’s sheer core count and the Ryzen’s higher clock speeds create vastly different performance profiles.

Head-to-Head Benchmarks

The head-to-head results are lopsided in the EPYC 7543P’s favor. In Cinebench R15 multicore, the EPYC scores 5,713 against the Ryzen’s 1,425, a 300.9% advantage. The single-core test tells a similar story: 806 versus 176, a 358% margin. These deltas grow even more extreme in Cinebench R23. The EPYC’s multicore result of 56,683 dwarfs the Ryzen’s 8,072, a 602.2% lead. The single-core R23 test shows 8,002 versus 1,142.5, a 600.4% gap.

The Ryzen 5 4600H does not register a single win across the four shared Cinebench tests. However, the Ryzen’s benchmark suite includes 3DMark and Passmark tests that the EPYC does not have in this comparison. The Ryzen’s 3DMark results show scaling from 675 in single-thread to 4,387 in 16 threads, with 4,355 at max threads. Its Passmark multithread score is 14,228, and its single-thread score is 2,418. These numbers, while not directly comparable to the EPYC’s Cinebench scores, indicate that the Ryzen is a capable performer in its own right, particularly for a mobile part.

The disparity in Cinebench scores reflects the architectural gap. The EPYC’s 32 cores and 64 threads provide a massive parallel throughput advantage, which Cinebench’s heavily threaded workloads reward. The Ryzen’s 6 cores and 12 threads cannot compete on raw multicore output, but its higher boost clock of 4.00 GHz versus the EPYC’s 3.70 GHz would normally suggest a single-core edge. The data shows the opposite: the EPYC wins single-core by 358% in R15 and 600.4% in R23. This counterintuitive result likely stems from the EPYC’s larger L3 cache and Zen 3’s improved IPC over Zen 2, though the cache difference is stark: 256 MB shared on the EPYC versus 8 MB shared on the Ryzen.

Architecture Differences

The two processors come from different Zen generations. The EPYC 7543P uses Zen 3, codenamed Milan, while the Ryzen 5 4600H uses Zen 2, codenamed Renoir. Both are built on TSMC’s 7 nm process, but the similarities end there. The EPYC packs 33,200 million transistors across an 8x 81 mm² die configuration, whereas the Ryzen integrates 9,800 million transistors on a single 156 mm² die.

The core counts diverge sharply: 32 cores and 64 threads on the EPYC versus 6 cores and 12 threads on the Ryzen. Base clocks favor the Ryzen at 3.00 GHz against the EPYC’s 2.80 GHz, and the boost clocks follow the same pattern at 4.00 GHz versus 3.70 GHz. Cache hierarchies differ dramatically. Both allocate 64 KB of L1 per core and 512 KB of L2 per core, but the L3 cache is a different beast: 256 MB shared on the EPYC versus 8 MB shared on the Ryzen.

Memory subsystems reflect their intended markets. The EPYC supports DDR4 over an eight-channel bus with 204.8 GB/s of bandwidth, while the Ryzen uses dual-channel DDR4 with 51.2 GB/s. The EPYC supports ECC memory; the Ryzen does not. PCIe generations differ, with the EPYC offering Gen 4 across 128 lanes (CPU only), while the Ryzen sticks with Gen 3. The Ryzen includes integrated Radeon RX Vega 6 graphics, while the EPYC has none. The EPYC uses Socket SP3, the Ryzen uses Socket FP6. The EPYC’s TDP is 225 W, the Ryzen’s is 45 W.

Both are currently marked as Active in production status. The EPYC launched on March 14, 2021, with a launch MSRP of $2730. The Ryzen launched on January 5, 2020, with no listed MSRP. Neither has an unlocked multiplier.

FAQ

Q: Which processor has a higher average benchmark score?

A: The AMD EPYC 7543P has an average benchmark score of 16,395, while the AMD Ryzen 5 4600H scores 16,341. The EPYC leads by 0.3%, which is within the noise of typical benchmarking variance.

Q: How many cores and threads does each CPU have?

A: The EPYC 7543P has 32 cores and 64 threads. The Ryzen 5 4600H has 6 cores and 12 threads.

Q: What is the L3 cache capacity difference?

A: The EPYC 7543P has 256 MB of shared L3 cache. The Ryzen 5 4600H has 8 MB of shared L3 cache. This 32x difference is the most prominent cache disparity.

Q: Which CPU supports ECC memory?

A: The EPYC 7543P supports ECC memory. The Ryzen 5 4600H does not support ECC.

Q: What are the memory bandwidth specifications?

A: The EPYC 7543P provides 204.8 GB/s over an eight-channel DDR4 bus. The Ryzen 5 4600H provides 51.2 GB/s over a dual-channel DDR4 bus.

Q: Do both CPUs have integrated graphics?

A: No. The Ryzen 5 4600H includes Radeon RX Vega 6 integrated graphics. The EPYC 7543P has no integrated graphics.

Specification Differences

| Specification | AMD EPYC 7543P | AMD Ryzen 5 4600H |

|---|---|---|

| Series | EPYC 7003 series | 4000 series |

| Cores | 32 | 6 |

| Threads | 64 | 12 |

| Base Clock | 2.80 GHz | 3.00 GHz |

| Boost Clock | 3.70 GHz | 4.00 GHz |

| TDP | 225 W | 45 W |

| Socket | AMD Socket SP3 | AMD Socket FP6 |

| Architecture | Zen 3 | Zen 2 |

| Codename | Milan | Renoir |

| Generation | EPYC (Zen 3 (Milan)) | Ryzen 5 (Zen 2 (Renoir)) |

| Transistors | 33,200 million | 9,800 million |

| Die Size | 8x 81 mm² | 156 mm² |

| L3 Cache | 256 MB (shared) | 8 MB (shared) |

| Memory Bus | Eight-channel | Dual-channel |

| Memory Bandwidth | 204.8 GB/s | 51.2 GB/s |

| ECC Memory | Yes | No |

| PCIe | Gen 4, 128 Lanes (CPU only) | Gen 3 |

| Integrated Graphics | None | Radeon RX Vega 6 |

| Market Segment | Server/Workstation | Mobile |

| Launch MSRP | $2730 | None |

| Part Number | 100-000000341100-100000341WOF | 100-000000100 |

Where Each One Wins

The EPYC 7543P wins decisively in every benchmark where the two overlap. Its Cinebench R15 multicore score of 5,713 is 4x the Ryzen’s 1,425. The R23 multicore gap is even wider, with the EPYC at 56,683 versus 8,072. For any workload that scales with core count—database serving, virtualization, scientific computing, content rendering—the EPYC is the clear choice. Its 64 threads and 256 MB of L3 cache provide massive parallel headroom. The eight-channel memory bus with 204.8 GB/s bandwidth further supports memory-intensive server tasks.

The Ryzen 5 4600H wins in the mobile segment by existing at all. Its 45 W TDP makes it suitable for laptops, whereas the EPYC’s 225 W TDP requires a server platform. The Ryzen’s integrated Radeon RX Vega 6 graphics mean it can operate without a discrete GPU, a capability the EPYC entirely lacks. Its higher boost clock of 4.00 GHz and lower base clock of 3.00 GHz suggest a design tuned for bursty single-threaded activity, though this does not translate to a win in the Cinebench single-core tests. The Ryzen’s 3DMark results, from 675 single-thread to 4,387 at 16 threads, show it handles gaming and general productivity workloads competently.

The data supports a split based on form factor and workload. The EPYC 7543P is for rack-mounted servers where power and cooling are plentiful and core count is paramount. The Ryzen 5 4600H is for thin-and-light laptops where battery life and thermals constrain the design. The Ryzen’s Passmark results—45,698 in integer math, 26,909 in floating point math, 20,2030 in data compression—demonstrate solid general-purpose performance. The EPYC’s single Cinebench R20 score of 23,806 in multicore reinforces its server pedigree.

Neither processor is a general-purpose winner across all scenarios. The EPYC’s 0.3% average score advantage over the Ryzen is statistically trivial, but the workload-specific gaps are enormous. For a database server running many concurrent queries, the EPYC’s 32 cores will crush the Ryzen. For a laptop user running a web browser and office applications, the Ryzen’s integrated graphics and lower power draw make it the only viable option. The choice is not about which is faster; it is about which fits the deployment target. The benchmark data confirms that the EPYC 7543P dominates in raw compute, while the Ryzen 5 4600H provides adequate performance in a mobile envelope.